Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0852

Experiment: 7H9 with Ethambutol 0.75 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0850 and Rv0851c overlap by 4 nucleotidesRv0851c and Rv0852 are separated by 90 nucleotidesRv0852 and Rv0853c are separated by 40 nucleotides Rv0850: Rv0850 - Putative transposase (fragment), at 947,312 to 947,644 Rv0850 Rv0851c: Rv0851c - Probable short-chain type dehydrogenase/reductase, at 947,641 to 948,468 Rv0851c Rv0852: Rv0852 - Possible fatty-acid-CoA ligase FadD16 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 948,559 to 949,395 Rv0852 Rv0853c: Rv0853c - Probable pyruvate or indole-3-pyruvate decarboxylase Pdc, at 949,436 to 951,118 Rv0853c Position (kb) 948 949 950Strain fitness (log2 ratio) -2 -1 0 1at 947.742 kb on - strand, within Rv0851cat 947.742 kb on - strand, within Rv0851cat 948.481 kb on + strandat 948.575 kb on - strandat 948.819 kb on + strand, within Rv0852at 948.935 kb on + strand, within Rv0852at 949.068 kb on + strand, within Rv0852at 949.068 kb on + strand, within Rv0852at 949.336 kb on + strandat 949.653 kb on + strand, within Rv0853cat 950.314 kb on - strand, within Rv0853c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ethambutol 0.75 ug/mL
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947,742 - Rv0851c 0.12 -2.6
947,742 - Rv0851c 0.12 -0.3
948,481 + -1.6
948,575 - -0.2
948,819 + Rv0852 0.31 -0.2
948,935 + Rv0852 0.45 +1.0
949,068 + Rv0852 0.61 +0.5
949,068 + Rv0852 0.61 +1.2
949,336 + +0.1
949,653 + Rv0853c 0.13 -0.4
950,314 - Rv0853c 0.52 +0.1

Or see this region's nucleotide sequence