Experiment: 7H9 with Ethambutol 0.75 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0157 and Rv0157A are separated by 15 nucleotides Rv0157A and Rv0158 are separated by 161 nucleotides Rv0158 and Rv0159c are separated by 3 nucleotides Rv0159c and Rv0160c are separated by 91 nucleotides
Rv0157: Rv0157 - Probable NAD(P) transhydrogenase (subunit beta) PntB [integral membrane protein] (pyridine nucleotide transhydrogenase subunit beta) (nicotinamide nucleotide transhydrogenase subunit beta), at 185,052 to 186,479
Rv0157
Rv0157A: Rv0157A - Conserved protein, at 186,495 to 186,623
Rv0157A
Rv0158: Rv0158 - Probable transcriptional regulatory protein (possibly TetR-family), at 186,785 to 187,429
Rv0158
Rv0159c: Rv0159c - PE family protein PE3, at 187,433 to 188,839
Rv0159c
Rv0160c: Rv0160c - PE family protein PE4, at 188,931 to 190,439
Rv0160c
Position (kb)
187
188
189 Strain fitness (log2 ratio)
-2
-1
0
1
2
3
4 at 186.477 kb on + strand at 186.478 kb on - strand at 186.478 kb on - strand at 186.508 kb on + strand, within Rv0157A at 186.509 kb on - strand, within Rv0157A at 186.781 kb on - strand at 186.814 kb on - strand at 186.853 kb on - strand, within Rv0158 at 186.929 kb on + strand, within Rv0158 at 186.930 kb on - strand, within Rv0158 at 186.930 kb on - strand, within Rv0158 at 186.935 kb on + strand, within Rv0158 at 186.935 kb on + strand, within Rv0158 at 186.935 kb on + strand, within Rv0158 at 186.935 kb on + strand, within Rv0158 at 186.936 kb on - strand, within Rv0158 at 186.971 kb on + strand, within Rv0158 at 187.043 kb on + strand, within Rv0158 at 187.103 kb on + strand, within Rv0158 at 187.121 kb on + strand, within Rv0158 at 187.121 kb on + strand, within Rv0158 at 187.121 kb on + strand, within Rv0158 at 187.122 kb on - strand, within Rv0158 at 187.185 kb on - strand, within Rv0158 at 187.195 kb on - strand, within Rv0158 at 187.195 kb on - strand, within Rv0158 at 187.195 kb on - strand, within Rv0158 at 187.235 kb on + strand, within Rv0158 at 187.269 kb on - strand, within Rv0158 at 187.292 kb on + strand, within Rv0158 at 187.292 kb on + strand, within Rv0158 at 187.551 kb on + strand at 187.557 kb on + strand at 187.557 kb on + strand at 187.557 kb on + strand at 187.557 kb on + strand at 187.558 kb on - strand at 187.558 kb on - strand at 187.558 kb on - strand at 187.558 kb on - strand at 187.558 kb on - strand at 187.558 kb on - strand at 187.561 kb on + strand at 187.561 kb on + strand at 187.562 kb on - strand at 187.562 kb on - strand at 187.562 kb on - strand at 187.562 kb on - strand at 187.569 kb on - strand at 187.598 kb on + strand, within Rv0159c at 187.598 kb on + strand, within Rv0159c at 187.599 kb on - strand, within Rv0159c at 187.599 kb on - strand, within Rv0159c at 187.599 kb on - strand, within Rv0159c at 187.599 kb on - strand, within Rv0159c at 187.599 kb on - strand, within Rv0159c at 187.599 kb on - strand, within Rv0159c at 187.601 kb on + strand, within Rv0159c at 187.602 kb on - strand, within Rv0159c at 187.694 kb on + strand, within Rv0159c at 187.694 kb on + strand, within Rv0159c at 187.694 kb on + strand, within Rv0159c at 187.695 kb on - strand, within Rv0159c at 187.710 kb on + strand, within Rv0159c at 187.710 kb on + strand, within Rv0159c at 187.717 kb on - strand, within Rv0159c at 187.730 kb on + strand, within Rv0159c at 187.730 kb on + strand, within Rv0159c at 187.731 kb on - strand, within Rv0159c at 187.739 kb on + strand, within Rv0159c at 187.739 kb on + strand, within Rv0159c at 187.776 kb on - strand, within Rv0159c at 187.776 kb on - strand, within Rv0159c at 187.833 kb on + strand, within Rv0159c at 187.833 kb on + strand, within Rv0159c at 187.833 kb on + strand, within Rv0159c at 187.833 kb on + strand, within Rv0159c at 187.833 kb on + strand, within Rv0159c at 187.833 kb on + strand, within Rv0159c at 187.833 kb on + strand, within Rv0159c at 187.834 kb on - strand, within Rv0159c at 187.834 kb on - strand, within Rv0159c at 187.834 kb on - strand, within Rv0159c at 187.834 kb on - strand, within Rv0159c at 187.836 kb on + strand, within Rv0159c at 187.836 kb on + strand, within Rv0159c at 187.836 kb on + strand, within Rv0159c at 187.836 kb on + strand, within Rv0159c at 187.836 kb on + strand, within Rv0159c at 187.837 kb on - strand, within Rv0159c at 187.837 kb on - strand, within Rv0159c at 187.837 kb on - strand, within Rv0159c at 187.911 kb on + strand, within Rv0159c at 187.964 kb on - strand, within Rv0159c at 187.964 kb on - strand, within Rv0159c at 187.992 kb on + strand, within Rv0159c at 187.993 kb on - strand, within Rv0159c at 188.001 kb on + strand, within Rv0159c at 188.001 kb on + strand, within Rv0159c at 188.001 kb on + strand, within Rv0159c at 188.013 kb on + strand, within Rv0159c at 188.013 kb on + strand, within Rv0159c at 188.013 kb on + strand, within Rv0159c at 188.013 kb on + strand, within Rv0159c at 188.014 kb on - strand, within Rv0159c at 188.014 kb on - strand, within Rv0159c at 188.014 kb on - strand, within Rv0159c at 188.020 kb on - strand, within Rv0159c at 188.020 kb on - strand, within Rv0159c at 188.020 kb on - strand, within Rv0159c at 188.020 kb on - strand, within Rv0159c at 188.082 kb on + strand, within Rv0159c at 188.094 kb on + strand, within Rv0159c at 188.094 kb on + strand, within Rv0159c at 188.094 kb on + strand, within Rv0159c at 188.128 kb on + strand, within Rv0159c at 188.129 kb on - strand, within Rv0159c at 188.131 kb on + strand, within Rv0159c at 188.132 kb on - strand, within Rv0159c at 188.191 kb on + strand, within Rv0159c at 188.202 kb on - strand, within Rv0159c at 188.367 kb on + strand, within Rv0159c at 188.443 kb on + strand, within Rv0159c at 188.444 kb on - strand, within Rv0159c at 188.548 kb on + strand, within Rv0159c at 188.548 kb on + strand, within Rv0159c at 188.548 kb on + strand, within Rv0159c at 188.549 kb on - strand, within Rv0159c at 188.642 kb on + strand, within Rv0159c at 188.833 kb on - strand at 188.833 kb on - strand at 188.995 kb on - strand at 188.995 kb on - strand at 188.995 kb on - strand at 189.023 kb on - strand at 189.061 kb on + strand at 189.061 kb on + strand at 189.061 kb on + strand at 189.062 kb on - strand at 189.062 kb on - strand at 189.062 kb on - strand at 189.062 kb on - strand at 189.160 kb on + strand, within Rv0160c at 189.220 kb on + strand, within Rv0160c at 189.221 kb on - strand, within Rv0160c at 189.248 kb on - strand, within Rv0160c at 189.364 kb on + strand, within Rv0160c at 189.364 kb on + strand, within Rv0160c at 189.364 kb on + strand, within Rv0160c at 189.364 kb on + strand, within Rv0160c at 189.364 kb on + strand, within Rv0160c at 189.364 kb on + strand, within Rv0160c at 189.364 kb on + strand, within Rv0160c at 189.365 kb on - strand, within Rv0160c at 189.365 kb on - strand, within Rv0160c at 189.365 kb on - strand, within Rv0160c at 189.365 kb on - strand, within Rv0160c at 189.365 kb on - strand, within Rv0160c at 189.365 kb on - strand, within Rv0160c at 189.368 kb on - strand, within Rv0160c at 189.384 kb on - strand, within Rv0160c at 189.386 kb on - strand, within Rv0160c at 189.445 kb on + strand, within Rv0160c at 189.460 kb on + strand, within Rv0160c at 189.460 kb on + strand, within Rv0160c at 189.461 kb on - strand, within Rv0160c at 189.547 kb on + strand, within Rv0160c at 189.547 kb on + strand, within Rv0160c at 189.570 kb on - strand, within Rv0160c at 189.617 kb on - strand, within Rv0160c at 189.617 kb on - strand, within Rv0160c at 189.686 kb on + strand, within Rv0160c at 189.731 kb on - strand, within Rv0160c at 189.731 kb on - strand, within Rv0160c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ethambutol 0.75 ug/mL remove 186,477 + -0.2 186,478 - +0.4 186,478 - -1.4 186,508 + Rv0157A 0.10 -0.0 186,509 - Rv0157A 0.11 -0.9 186,781 - -0.7 186,814 - -0.5 186,853 - Rv0158 0.11 -0.0 186,929 + Rv0158 0.22 -0.2 186,930 - Rv0158 0.22 -0.3 186,930 - Rv0158 0.22 -2.0 186,935 + Rv0158 0.23 -0.2 186,935 + Rv0158 0.23 +0.2 186,935 + Rv0158 0.23 -0.4 186,935 + Rv0158 0.23 -0.4 186,936 - Rv0158 0.23 -0.3 186,971 + Rv0158 0.29 +0.2 187,043 + Rv0158 0.40 +0.4 187,103 + Rv0158 0.49 -0.6 187,121 + Rv0158 0.52 -1.3 187,121 + Rv0158 0.52 -1.9 187,121 + Rv0158 0.52 -0.1 187,122 - Rv0158 0.52 -0.7 187,185 - Rv0158 0.62 -0.5 187,195 - Rv0158 0.64 +0.2 187,195 - Rv0158 0.64 +0.2 187,195 - Rv0158 0.64 -0.3 187,235 + Rv0158 0.70 -0.2 187,269 - Rv0158 0.75 +0.1 187,292 + Rv0158 0.79 -1.2 187,292 + Rv0158 0.79 -0.2 187,551 + -0.2 187,557 + +0.7 187,557 + -0.3 187,557 + +0.2 187,557 + +0.4 187,558 - +0.4 187,558 - +0.3 187,558 - -0.2 187,558 - -0.2 187,558 - -0.3 187,558 - -0.2 187,561 + +1.5 187,561 + +0.1 187,562 - -0.1 187,562 - -0.8 187,562 - -0.1 187,562 - +0.2 187,569 - +0.0 187,598 + Rv0159c 0.12 -1.2 187,598 + Rv0159c 0.12 -0.3 187,599 - Rv0159c 0.12 -0.6 187,599 - Rv0159c 0.12 +0.0 187,599 - Rv0159c 0.12 +1.0 187,599 - Rv0159c 0.12 +3.5 187,599 - Rv0159c 0.12 +0.7 187,599 - Rv0159c 0.12 +0.6 187,601 + Rv0159c 0.12 -0.5 187,602 - Rv0159c 0.12 +0.1 187,694 + Rv0159c 0.19 +1.5 187,694 + Rv0159c 0.19 +2.0 187,694 + Rv0159c 0.19 -0.1 187,695 - Rv0159c 0.19 -0.0 187,710 + Rv0159c 0.20 +0.9 187,710 + Rv0159c 0.20 -0.4 187,717 - Rv0159c 0.20 -0.1 187,730 + Rv0159c 0.21 -0.0 187,730 + Rv0159c 0.21 -0.4 187,731 - Rv0159c 0.21 +0.3 187,739 + Rv0159c 0.22 -0.2 187,739 + Rv0159c 0.22 +0.3 187,776 - Rv0159c 0.24 -0.5 187,776 - Rv0159c 0.24 +0.1 187,833 + Rv0159c 0.28 -0.4 187,833 + Rv0159c 0.28 -0.2 187,833 + Rv0159c 0.28 -0.2 187,833 + Rv0159c 0.28 -0.4 187,833 + Rv0159c 0.28 -0.0 187,833 + Rv0159c 0.28 +2.0 187,833 + Rv0159c 0.28 -0.4 187,834 - Rv0159c 0.29 -1.5 187,834 - Rv0159c 0.29 -0.5 187,834 - Rv0159c 0.29 -0.4 187,834 - Rv0159c 0.29 -0.2 187,836 + Rv0159c 0.29 -0.1 187,836 + Rv0159c 0.29 -0.8 187,836 + Rv0159c 0.29 -0.3 187,836 + Rv0159c 0.29 -0.7 187,836 + Rv0159c 0.29 +2.0 187,837 - Rv0159c 0.29 -0.5 187,837 - Rv0159c 0.29 +0.1 187,837 - Rv0159c 0.29 +0.0 187,911 + Rv0159c 0.34 +0.2 187,964 - Rv0159c 0.38 -0.7 187,964 - Rv0159c 0.38 -1.2 187,992 + Rv0159c 0.40 +0.1 187,993 - Rv0159c 0.40 -0.4 188,001 + Rv0159c 0.40 +0.3 188,001 + Rv0159c 0.40 -0.4 188,001 + Rv0159c 0.40 +0.3 188,013 + Rv0159c 0.41 -2.2 188,013 + Rv0159c 0.41 +0.1 188,013 + Rv0159c 0.41 +0.0 188,013 + Rv0159c 0.41 +0.1 188,014 - Rv0159c 0.41 -0.3 188,014 - Rv0159c 0.41 +1.3 188,014 - Rv0159c 0.41 -0.1 188,020 - Rv0159c 0.42 +0.4 188,020 - Rv0159c 0.42 -0.2 188,020 - Rv0159c 0.42 -0.2 188,020 - Rv0159c 0.42 -0.2 188,082 + Rv0159c 0.46 -0.2 188,094 + Rv0159c 0.47 -0.2 188,094 + Rv0159c 0.47 +0.4 188,094 + Rv0159c 0.47 -0.2 188,128 + Rv0159c 0.49 +0.3 188,129 - Rv0159c 0.49 -0.5 188,131 + Rv0159c 0.50 -1.0 188,132 - Rv0159c 0.50 -0.1 188,191 + Rv0159c 0.54 +1.4 188,202 - Rv0159c 0.55 -0.2 188,367 + Rv0159c 0.66 +1.4 188,443 + Rv0159c 0.72 +0.0 188,444 - Rv0159c 0.72 -0.0 188,548 + Rv0159c 0.79 -0.0 188,548 + Rv0159c 0.79 +0.6 188,548 + Rv0159c 0.79 -0.0 188,549 - Rv0159c 0.79 +1.5 188,642 + Rv0159c 0.86 +0.8 188,833 - -0.2 188,833 - +0.4 188,995 - -1.5 188,995 - +0.3 188,995 - +0.0 189,023 - -0.1 189,061 + -0.0 189,061 + -0.0 189,061 + -0.0 189,062 - -0.3 189,062 - -0.1 189,062 - -0.1 189,062 - +0.2 189,160 + Rv0160c 0.15 +1.0 189,220 + Rv0160c 0.19 -0.7 189,221 - Rv0160c 0.19 +0.3 189,248 - Rv0160c 0.21 +1.5 189,364 + Rv0160c 0.29 -0.4 189,364 + Rv0160c 0.29 +0.0 189,364 + Rv0160c 0.29 -0.7 189,364 + Rv0160c 0.29 +0.8 189,364 + Rv0160c 0.29 -0.3 189,364 + Rv0160c 0.29 +0.1 189,364 + Rv0160c 0.29 +1.0 189,365 - Rv0160c 0.29 -0.3 189,365 - Rv0160c 0.29 +0.1 189,365 - Rv0160c 0.29 -0.6 189,365 - Rv0160c 0.29 +4.0 189,365 - Rv0160c 0.29 -0.3 189,365 - Rv0160c 0.29 -0.0 189,368 - Rv0160c 0.29 +2.0 189,384 - Rv0160c 0.30 -0.2 189,386 - Rv0160c 0.30 +0.1 189,445 + Rv0160c 0.34 +0.3 189,460 + Rv0160c 0.35 +0.8 189,460 + Rv0160c 0.35 +1.1 189,461 - Rv0160c 0.35 -0.0 189,547 + Rv0160c 0.41 -0.2 189,547 + Rv0160c 0.41 -0.0 189,570 - Rv0160c 0.42 -0.1 189,617 - Rv0160c 0.45 -0.5 189,617 - Rv0160c 0.45 +3.3 189,686 + Rv0160c 0.50 -1.1 189,731 - Rv0160c 0.53 +0.1 189,731 - Rv0160c 0.53 -0.0
Or see this region's nucleotide sequence