Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3533c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
3,969,766	+		Rv3532	0.35	-0.1
3,969,802	+		Rv3532	0.38	-0.2
3,969,802	+		Rv3532	0.38	-1.0
3,969,802	+		Rv3532	0.38	-0.0
3,969,803	-		Rv3532	0.38	-0.5
3,969,803	-		Rv3532	0.38	+1.4
3,969,803	-		Rv3532	0.38	+0.1
3,969,809	-		Rv3532	0.38	+0.4
3,969,849	+		Rv3532	0.41	+1.8
3,969,849	+		Rv3532	0.41	+0.2
3,969,849	+		Rv3532	0.41	-2.2
3,969,850	-		Rv3532	0.42	+0.2
3,969,850	-		Rv3532	0.42	-0.6
3,969,850	-		Rv3532	0.42	+0.2
3,969,850	-		Rv3532	0.42	-2.6
3,970,194	-		Rv3532	0.70	+0.1
3,970,523	+				-1.8
3,970,523	+				-0.4
3,970,524	-				+0.5
3,970,637	+				+0.6
3,970,637	+				-0.5
3,970,638	-				-0.8
3,970,638	-				+0.1
3,970,640	+				-0.2
3,970,641	-				-0.2
3,970,786	+				-0.4
3,971,067	+		Rv3533c	0.21	-0.1
3,971,098	-		Rv3533c	0.22	-1.0
3,971,191	+		Rv3533c	0.28	-0.1
3,971,217	+		Rv3533c	0.29	-0.6
3,971,217	+		Rv3533c	0.29	-0.3
3,971,281	-		Rv3533c	0.33	-0.2
3,971,281	-		Rv3533c	0.33	-0.4
3,971,994	-		Rv3533c	0.74	+0.1
3,971,994	-		Rv3533c	0.74	+1.3
3,972,035	+		Rv3533c	0.76	-1.2
3,972,036	-		Rv3533c	0.76	-0.7
3,972,240	-		Rv3533c	0.88	+1.8
3,972,240	-		Rv3533c	0.88	-0.5
3,972,240	-		Rv3533c	0.88	+0.6
3,972,420	-				+0.2
3,972,423	+				+0.3
3,972,423	+				-0.0
3,972,424	-				-0.0
3,972,446	+				-0.9
3,972,686	-		Rv3534c	0.13	-0.4
3,972,728	-		Rv3534c	0.17	-0.1
3,972,740	-		Rv3534c	0.18	+0.2
3,973,100	-		Rv3534c	0.53	-0.6
3,973,100	-		Rv3534c	0.53	-0.3
3,973,414	+		Rv3534c	0.83	-0.6
3,973,414	+		Rv3534c	0.83	+0.1
3,973,414	+		Rv3534c	0.83	-0.3
3,973,415	-		Rv3534c	0.83	+0.9
3,973,415	-		Rv3534c	0.83	+1.4