Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2696c and Rv2697c are separated by 74 nucleotides Rv2697c and Rv2698 are separated by 25 nucleotides Rv2698 and Rv2699c are separated by 4 nucleotides
Rv2696c: Rv2696c - Conserved alanine and glycine and valine rich protein, at 3,012,829 to 3,013,608
Rv2696c
Rv2697c: Rv2697c - Probable deoxyuridine 5'-triphosphate nucleotidohydrolase Dut (dUTPase) (dUTP pyrophosphatase) (deoxyuridine 5'-triphosphatase) (dUTP diphosphatase) (deoxyuridine-triphosphatase), at 3,013,683 to 3,014,147
Rv2697c
Rv2698: Rv2698 - Probable conserved alanine rich transmembrane protein, at 3,014,173 to 3,014,658
Rv2698
Rv2699c: Rv2699c - Conserved hypothetical protein, at 3,014,663 to 3,014,965
Rv2699c
Position (kb)
3013
3014
3015 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 3012.716 kb on + strand at 3012.716 kb on + strand at 3012.717 kb on - strand at 3012.717 kb on - strand at 3012.742 kb on + strand at 3012.810 kb on + strand at 3012.811 kb on - strand at 3012.811 kb on - strand at 3012.811 kb on - strand at 3012.943 kb on + strand, within Rv2696c at 3012.944 kb on - strand, within Rv2696c at 3013.264 kb on - strand, within Rv2696c at 3013.355 kb on - strand, within Rv2696c at 3014.661 kb on + strand at 3014.661 kb on + strand at 3014.662 kb on - strand at 3015.073 kb on - strand at 3015.100 kb on - strand at 3015.100 kb on - strand at 3015.100 kb on - strand at 3015.135 kb on + strand at 3015.136 kb on - strand at 3015.136 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 3,012,716 + -0.4 3,012,716 + +0.1 3,012,717 - -0.3 3,012,717 - -0.4 3,012,742 + -0.2 3,012,810 + +1.2 3,012,811 - +0.5 3,012,811 - +1.8 3,012,811 - -0.4 3,012,943 + Rv2696c 0.15 -1.6 3,012,944 - Rv2696c 0.15 +1.8 3,013,264 - Rv2696c 0.56 -3.3 3,013,355 - Rv2696c 0.67 -1.9 3,014,661 + -1.2 3,014,661 + -0.7 3,014,662 - -0.2 3,015,073 - -0.5 3,015,100 - -0.4 3,015,100 - -1.7 3,015,100 - -0.1 3,015,135 + -0.1 3,015,136 - +0.4 3,015,136 - -0.5
Or see this region's nucleotide sequence