Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2368c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
2,648,091	-		Rv2366c	0.79	+2.4
2,648,091	-		Rv2366c	0.79	-1.0
2,648,218	-		Rv2366c	0.89	+0.1
2,648,255	-				-0.2
2,648,255	-				-0.6
2,648,255	-				-0.9
2,648,255	-				-0.4
2,648,255	-				-3.3
2,648,355	-				-0.4
2,648,355	-				-0.2
2,648,378	-				-0.2
2,648,378	-				-2.2
2,648,432	-		Rv2367c	0.12	+0.0
2,648,432	-		Rv2367c	0.12	+0.6
2,648,898	-				-0.1
2,648,898	-				-0.3
2,648,992	+				-0.2
2,649,257	+		Rv2368c	0.32	+0.3
2,649,269	-		Rv2368c	0.33	+1.8
2,649,353	-		Rv2368c	0.41	+0.2
2,649,353	-		Rv2368c	0.41	-0.3
2,649,363	+		Rv2368c	0.42	+0.4
2,649,363	+		Rv2368c	0.42	-0.1
2,649,364	-		Rv2368c	0.42	+0.3
2,649,368	-		Rv2368c	0.43	+0.2
2,649,368	-		Rv2368c	0.43	-0.5
2,649,368	-		Rv2368c	0.43	+1.5
2,649,448	-		Rv2368c	0.50	+0.7
2,649,502	+		Rv2368c	0.55	-0.4
2,649,502	+		Rv2368c	0.55	+0.5
2,649,503	-		Rv2368c	0.55	+0.0
2,649,694	-		Rv2368c	0.73	-0.1
2,649,871	-				-0.7
2,650,047	+		Rv2369c	0.33	-0.5
2,650,307	+				+0.2
2,650,307	+				-0.2
2,650,446	+		Rv2370c	0.15	-0.0
2,650,447	-		Rv2370c	0.15	-1.2
2,650,470	+		Rv2370c	0.17	-0.3
2,650,470	+		Rv2370c	0.17	+0.2
2,650,471	-		Rv2370c	0.17	-0.5
2,650,471	-		Rv2370c	0.17	-0.3
2,650,473	+		Rv2370c	0.17	-0.2
2,650,513	+		Rv2370c	0.20	-0.2
2,650,514	-		Rv2370c	0.20	-0.9
2,650,514	-		Rv2370c	0.20	-0.0
2,650,521	+		Rv2370c	0.21	-0.3
2,650,824	+		Rv2370c	0.44	-0.5
2,650,940	-		Rv2370c	0.53	-0.0
2,650,940	-		Rv2370c	0.53	+0.0