Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2068c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
2,324,909	-		Rv2067c	0.21	-0.2
2,324,912	+		Rv2067c	0.22	-0.1
2,324,912	+		Rv2067c	0.22	-0.2
2,324,913	-		Rv2067c	0.22	-0.8
2,324,949	-		Rv2067c	0.25	-0.1
2,324,949	-		Rv2067c	0.25	+0.7
2,325,066	-		Rv2067c	0.34	-0.1
2,325,101	+		Rv2067c	0.37	-0.5
2,325,102	-		Rv2067c	0.37	-1.3
2,325,281	-		Rv2067c	0.52	+0.3
2,325,384	-		Rv2067c	0.60	+0.5
2,325,384	-		Rv2067c	0.60	-0.1
2,325,616	-		Rv2067c	0.79	-0.2
2,325,828	-				+0.4
2,325,887	+				+1.5
2,325,887	+				-0.1
2,325,887	+				-0.7
2,325,992	+		Rv2068c	0.11	+0.9
2,325,992	+		Rv2068c	0.11	+0.0
2,325,993	-		Rv2068c	0.12	+0.5
2,326,224	+		Rv2068c	0.37	+0.8
2,326,311	-		Rv2068c	0.46	+0.0
2,326,311	-		Rv2068c	0.46	-0.8
2,326,387	-		Rv2068c	0.54	-0.0
2,326,387	-		Rv2068c	0.54	+0.3
2,326,388	+		Rv2068c	0.54	+0.3
2,326,388	+		Rv2068c	0.54	+0.3
2,326,389	-		Rv2068c	0.54	+0.1
2,326,393	+		Rv2068c	0.55	+0.3
2,326,393	+		Rv2068c	0.55	-1.3
2,326,484	+		Rv2068c	0.65	-0.4
2,326,484	+		Rv2068c	0.65	-0.8
2,326,485	-		Rv2068c	0.65	-0.5
2,326,625	+		Rv2068c	0.80	+2.1
2,326,625	+		Rv2068c	0.80	-1.1
2,326,625	+		Rv2068c	0.80	+0.4
2,326,625	+		Rv2068c	0.80	+1.8
2,326,625	+		Rv2068c	0.80	+0.4
2,326,625	+		Rv2068c	0.80	+0.2
2,326,626	-		Rv2068c	0.80	+0.3
2,326,626	-		Rv2068c	0.80	-1.9
2,326,626	-		Rv2068c	0.80	-1.5
2,326,626	-		Rv2068c	0.80	-0.1
2,326,626	-		Rv2068c	0.80	+0.5
2,326,626	-		Rv2068c	0.80	-0.2
2,326,626	-		Rv2068c	0.80	+0.2
2,326,626	-		Rv2068c	0.80	+0.1
2,326,646	+		Rv2068c	0.82	+0.1
2,326,646	+		Rv2068c	0.82	+0.3
2,326,647	-		Rv2068c	0.82	+0.3
2,326,647	-		Rv2068c	0.82	+0.2
2,326,647	-		Rv2068c	0.82	-0.3
2,326,814	+				+1.8
2,326,815	-				-0.3
2,326,815	-				-0.2
2,326,815	-				-1.0
2,326,817	+				-0.5
2,326,818	-				+0.8
2,326,818	-				-0.4
2,326,818	-				-0.6
2,326,893	-				+0.6
2,326,907	+				-0.4
2,326,930	+				+2.4
2,326,937	+				-0.5
2,326,937	+				-0.7
2,326,938	-				+0.5
2,327,030	+		Rv2069	0.15	-0.5
2,327,070	+		Rv2069	0.23	-0.0
2,327,070	+		Rv2069	0.23	-0.6
2,327,119	+		Rv2069	0.31	-0.8
2,327,120	-		Rv2069	0.32	-0.3
2,327,269	+		Rv2069	0.58	-1.1
2,327,269	+		Rv2069	0.58	-0.1
2,327,270	-		Rv2069	0.58	+1.8
2,327,706	-		Rv2070c	0.29	-0.9
2,327,712	-		Rv2070c	0.30	-0.6
2,327,725	+		Rv2070c	0.32	-0.4