Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1564c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,768,570	+		Rv1563c	0.62	-0.4
1,769,010	+		Rv1563c	0.82	-0.1
1,769,260	+				+0.7
1,769,916	+		Rv1564c	0.22	+0.1
1,770,216	-		Rv1564c	0.36	+1.0
1,770,638	-		Rv1564c	0.55	+0.4
1,771,009	+		Rv1564c	0.73	-0.1
1,771,009	+		Rv1564c	0.73	-1.1
1,771,117	+		Rv1564c	0.78	+0.8
1,771,118	-		Rv1564c	0.78	-0.4
1,771,219	+		Rv1564c	0.82	-0.1
1,771,220	-		Rv1564c	0.82	+1.1
1,771,225	+		Rv1564c	0.83	-0.6
1,771,225	+		Rv1564c	0.83	-0.6
1,771,225	+		Rv1564c	0.83	-0.1
1,771,226	-		Rv1564c	0.83	+0.0
1,771,226	-		Rv1564c	0.83	-0.5
1,771,378	+		Rv1564c	0.90	-0.2
1,771,378	+		Rv1564c	0.90	-0.2
1,771,379	-		Rv1564c	0.90	-0.5
1,771,379	-		Rv1564c	0.90	+0.2
1,771,452	+				+0.2
1,771,510	+				+0.2
1,771,613	-				-1.0
1,771,634	+				-0.3
1,771,634	+				+0.5
1,771,634	+				-2.4
1,771,635	-				-0.7
1,771,701	+				-2.1
1,771,701	+				-1.2
1,771,702	-				-1.6
1,772,013	+		Rv1565c	0.17	-1.2
1,772,014	-		Rv1565c	0.17	-0.2
1,772,014	-		Rv1565c	0.17	-1.3
1,772,140	-		Rv1565c	0.23	-1.8