Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0935

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,042,299	-		Rv0934	0.16	-0.5
1,042,436	+		Rv0934	0.29	+1.9
1,042,436	+		Rv0934	0.29	+0.2
1,042,453	+		Rv0934	0.30	+0.9
1,042,454	-		Rv0934	0.30	+1.0
1,042,514	+		Rv0934	0.35	+0.8
1,042,514	+		Rv0934	0.35	+0.7
1,042,515	-		Rv0934	0.36	+0.0
1,042,575	-		Rv0934	0.41	-0.2
1,042,706	+		Rv0934	0.53	+0.9
1,042,707	-		Rv0934	0.53	-0.1
1,042,911	+		Rv0934	0.71	+1.5
1,042,918	+		Rv0934	0.71	-1.0
1,042,919	-		Rv0934	0.71	+0.0
1,043,054	+		Rv0934	0.83	-2.4
1,043,055	-		Rv0934	0.84	+0.2
1,043,360	+				-0.8
1,043,360	+				+0.7
1,043,360	+				-0.6
1,043,361	-				-0.6
1,043,361	-				+2.9
1,043,488	+		Rv0935	0.19	-0.2
1,043,615	+		Rv0935	0.31	-0.3
1,043,675	+		Rv0935	0.37	+0.7
1,043,675	+		Rv0935	0.37	+0.2
1,043,676	-		Rv0935	0.37	+0.1
1,043,809	+		Rv0935	0.50	+0.1
1,043,810	-		Rv0935	0.50	-0.5
1,043,810	-		Rv0935	0.50	-0.2
1,043,887	-		Rv0935	0.58	+0.7
1,044,115	+		Rv0935	0.80	+0.2
1,044,116	-		Rv0935	0.80	+0.5
1,044,116	-		Rv0935	0.80	-0.4
1,044,246	+				+0.3
1,044,247	-				-0.6
1,044,351	+				-0.2
1,044,386	+				-0.4
1,044,386	+				-0.2
1,044,752	+		Rv0936	0.48	-0.8
1,044,753	-		Rv0936	0.48	-0.1
1,044,815	+		Rv0936	0.55	-0.6
1,044,816	-		Rv0936	0.55	-0.3