Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0908

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,010,761	-		Rv0907	0.39	+0.4
1,010,853	+		Rv0907	0.45	-0.6
1,010,877	-		Rv0907	0.46	-0.1
1,011,015	-		Rv0907	0.55	-0.8
1,011,015	-		Rv0907	0.55	-0.6
1,011,060	+		Rv0907	0.58	-1.8
1,012,298	+		Rv0908	0.24	-0.4
1,012,876	+		Rv0908	0.48	+0.2
1,013,527	+		Rv0908	0.75	-1.3
1,013,538	-		Rv0908	0.75	-0.5
1,013,578	-		Rv0908	0.77	-0.2
1,013,757	+		Rv0908	0.85	+0.6
1,013,758	-		Rv0908	0.85	-1.0
1,013,787	-		Rv0908	0.86	+0.1
1,013,787	-		Rv0908	0.86	-0.9
1,013,798	+		Rv0908	0.86	-0.0
1,013,878	-		Rv0908	0.90	-0.2
1,013,951	+				+1.3
1,013,952	-				-0.3
1,014,143	+				+0.7
1,014,253	-				+0.3
1,014,253	-				-0.5
1,014,405	+				-0.0
1,014,406	-				+0.4
1,014,406	-				+0.7
1,014,554	-				+0.0
1,014,630	-				+1.2
1,014,630	-				+0.3
1,014,646	+				-0.1
1,014,676	+				-0.0
1,014,700	+		Rv0909	0.11	+0.9
1,014,790	-		Rv0909	0.61	+0.5