Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3825c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
4,292,260	-		Rv3824c	0.40	+0.4
4,292,523	-		Rv3824c	0.58	+0.9
4,292,606	+		Rv3824c	0.63	+0.8
4,292,607	-		Rv3824c	0.63	+0.8
4,292,638	+		Rv3824c	0.65	+0.7
4,292,678	+		Rv3824c	0.68	-0.6
4,292,678	+		Rv3824c	0.68	-0.0
4,292,919	-		Rv3824c	0.83	-0.6
4,292,919	-		Rv3824c	0.83	+0.4
4,293,034	+				+0.2
4,293,035	-				-0.4
4,293,039	-				+0.5
4,293,112	+				-0.4
4,293,158	-				-0.0
4,293,166	+				+1.9
4,293,178	+				-0.2
4,293,186	-				+0.3
4,293,205	-				-0.2
4,293,208	+				+0.7
4,293,209	-				+0.3
4,293,209	-				+0.9
4,293,278	-				+0.3
4,293,369	+				+0.2
4,293,624	-				+0.2
4,293,624	-				-0.3
4,293,661	+				-0.4
4,293,662	-				-1.4
4,293,691	+				-0.2
4,293,691	+				-0.0
4,293,691	+				+0.2
4,293,692	-				+0.3
4,293,692	-				+1.9
4,293,851	-				+0.4
4,294,257	+		Rv3825c	0.16	+0.1
4,294,258	-		Rv3825c	0.16	+0.3
4,294,258	-		Rv3825c	0.16	+1.8
4,294,285	+		Rv3825c	0.17	+0.8
4,294,285	+		Rv3825c	0.17	+1.0
4,294,285	+		Rv3825c	0.17	+0.7
4,294,286	-		Rv3825c	0.17	+0.4
4,294,286	-		Rv3825c	0.17	+0.8
4,294,432	+		Rv3825c	0.19	+0.1
4,294,478	+		Rv3825c	0.20	+0.6
4,294,481	-		Rv3825c	0.20	-0.1
4,294,549	+		Rv3825c	0.21	-1.6
4,294,550	-		Rv3825c	0.21	+0.4
4,294,600	+		Rv3825c	0.22	+0.3
4,294,600	+		Rv3825c	0.22	+0.1
4,294,600	+		Rv3825c	0.22	+0.3
4,294,601	-		Rv3825c	0.22	-0.1
4,294,601	-		Rv3825c	0.22	+0.6
4,294,776	-		Rv3825c	0.24	+0.3
4,294,791	+		Rv3825c	0.25	+1.3
4,294,896	+		Rv3825c	0.26	+0.1
4,294,896	+		Rv3825c	0.26	+1.0
4,294,896	+		Rv3825c	0.26	-0.1
4,294,942	+		Rv3825c	0.27	+0.2
4,295,196	+		Rv3825c	0.31	+0.1
4,295,196	+		Rv3825c	0.31	+0.3
4,295,196	+		Rv3825c	0.31	+1.6
4,295,197	-		Rv3825c	0.31	+0.8
4,295,197	-		Rv3825c	0.31	-0.4
4,295,197	-		Rv3825c	0.31	+0.5
4,295,283	+		Rv3825c	0.32	-0.1
4,295,545	-		Rv3825c	0.36	-0.0
4,295,620	+		Rv3825c	0.38	+0.2
4,295,620	+		Rv3825c	0.38	+1.0
4,295,621	-		Rv3825c	0.38	-0.1
4,295,621	-		Rv3825c	0.38	+1.8
4,295,621	-		Rv3825c	0.38	-0.1
4,295,686	+		Rv3825c	0.39	-0.3
4,295,686	+		Rv3825c	0.39	-0.9
4,295,687	-		Rv3825c	0.39	-0.4
4,295,687	-		Rv3825c	0.39	+0.7
4,295,760	-		Rv3825c	0.40	-0.2
4,295,771	+		Rv3825c	0.40	+0.3
4,295,787	+		Rv3825c	0.40	-0.4
4,295,787	+		Rv3825c	0.40	-0.2
4,295,788	-		Rv3825c	0.40	+0.2
4,295,985	+		Rv3825c	0.43	-0.3
4,295,985	+		Rv3825c	0.43	+1.7
4,296,139	+		Rv3825c	0.46	+0.3
4,296,140	-		Rv3825c	0.46	+0.3
4,296,169	+		Rv3825c	0.46	+0.9
4,296,169	+		Rv3825c	0.46	-1.4
4,296,170	-		Rv3825c	0.46	+0.2
4,296,170	-		Rv3825c	0.46	-0.2
4,296,204	+		Rv3825c	0.47	-0.1
4,296,204	+		Rv3825c	0.47	+0.3
4,296,212	+		Rv3825c	0.47	+0.5
4,296,217	-		Rv3825c	0.47	-1.5
4,296,286	+		Rv3825c	0.48	+0.1
4,296,287	-		Rv3825c	0.48	+0.4
4,296,287	-		Rv3825c	0.48	+0.5
4,296,364	+		Rv3825c	0.49	+0.2
4,296,364	+		Rv3825c	0.49	-0.0
4,296,397	+		Rv3825c	0.50	+0.0
4,296,397	+		Rv3825c	0.50	+0.1
4,296,397	+		Rv3825c	0.50	+0.4
4,296,397	+		Rv3825c	0.50	-0.0
4,296,398	-		Rv3825c	0.50	-0.1
4,296,398	-		Rv3825c	0.50	+0.8
4,296,398	-		Rv3825c	0.50	-2.0
4,296,469	-		Rv3825c	0.51	-0.1
4,296,760	-		Rv3825c	0.55	+3.9
4,296,919	+		Rv3825c	0.58	+0.4
4,296,919	+		Rv3825c	0.58	+0.3
4,296,920	-		Rv3825c	0.58	+0.1
4,296,920	-		Rv3825c	0.58	-0.1
4,296,920	-		Rv3825c	0.58	+0.3
4,297,098	+		Rv3825c	0.61	-0.0
4,297,098	+		Rv3825c	0.61	-0.8
4,297,098	+		Rv3825c	0.61	+0.9
4,297,099	-		Rv3825c	0.61	+0.1
4,297,237	+		Rv3825c	0.63	+0.4
4,297,237	+		Rv3825c	0.63	+0.3
4,297,288	+		Rv3825c	0.64	-0.7
4,297,289	-		Rv3825c	0.64	+0.7
4,297,291	+		Rv3825c	0.64	+0.1
4,297,335	+		Rv3825c	0.64	+0.7
4,297,336	-		Rv3825c	0.64	+0.6
4,297,518	+		Rv3825c	0.67	-1.1
4,297,545	+		Rv3825c	0.68	+0.4
4,297,546	-		Rv3825c	0.68	+1.3
4,297,546	-		Rv3825c	0.68	-0.5
4,297,626	+		Rv3825c	0.69	-0.3
4,297,627	-		Rv3825c	0.69	+0.0
4,297,855	-		Rv3825c	0.73	+1.0
4,297,855	-		Rv3825c	0.73	+1.4
4,297,942	-		Rv3825c	0.74	+0.5
4,297,984	+		Rv3825c	0.75	+0.4
4,297,985	-		Rv3825c	0.75	+0.3
4,298,075	+		Rv3825c	0.76	+1.3
4,298,076	-		Rv3825c	0.76	-0.6
4,298,076	-		Rv3825c	0.76	+0.9
4,298,096	-		Rv3825c	0.76	-0.2
4,298,096	-		Rv3825c	0.76	+1.6
4,298,305	+		Rv3825c	0.80	+0.8
4,298,432	+		Rv3825c	0.82	+0.1
4,298,432	+		Rv3825c	0.82	-0.1
4,298,433	-		Rv3825c	0.82	+0.7
4,298,433	-		Rv3825c	0.82	-0.0
4,298,475	+		Rv3825c	0.82	-0.3
4,298,557	+		Rv3825c	0.84	-1.6
4,298,557	+		Rv3825c	0.84	-0.1
4,298,557	+		Rv3825c	0.84	+0.1
4,298,557	+		Rv3825c	0.84	+0.9
4,298,558	-		Rv3825c	0.84	-1.7
4,298,579	-		Rv3825c	0.84	+0.4
4,298,579	-		Rv3825c	0.84	-0.7
4,298,674	+		Rv3825c	0.85	+0.2
4,298,754	+		Rv3825c	0.87	+0.6
4,299,106	+				-0.2
4,299,112	+				+0.5
4,299,154	+				+0.1
4,299,154	+				-0.7
4,299,154	+				+0.2
4,299,215	+				+1.1
4,299,336	-				+1.9
4,299,394	+				+0.7
4,299,395	-				+0.0
4,299,395	-				+1.1
4,299,395	-				-0.2
4,299,453	+				+0.3
4,299,453	+				+0.4
4,299,454	-				-1.9
4,299,519	-				+0.9
4,299,566	+				+1.2
4,299,567	-				+0.5
4,299,647	+				-0.4
4,299,647	+				-0.1
4,299,648	-				+0.8
4,299,670	+				-0.7
4,299,670	+				-0.3
4,299,677	-				-0.8
4,299,690	-				+1.3
4,299,707	+				-1.1
4,299,779	-				+1.9
4,299,884	+				+2.9
4,299,916	-				+1.1
4,300,131	+		Rv3826	0.18	+0.3
4,300,201	+		Rv3826	0.22	+0.4
4,300,252	-		Rv3826	0.25	+0.6
4,300,321	+		Rv3826	0.29	+0.5
4,300,515	+		Rv3826	0.40	+0.7
4,300,516	-		Rv3826	0.40	+0.2
4,300,516	-		Rv3826	0.40	+0.2