Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3819

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
4,283,005	-		Rv3818	0.36	-1.1
4,283,080	-		Rv3818	0.41	-1.0
4,283,138	-		Rv3818	0.44	-0.2
4,283,186	+		Rv3818	0.48	-0.0
4,283,736	+		Rv3818	0.83	-1.9
4,284,024	+				-1.0
4,284,155	-		Rv3819	0.47	-0.7
4,284,390	+				+0.6
4,284,433	+				-0.1
4,284,433	+				-0.4
4,284,434	-				+0.7
4,284,468	+				-1.6
4,284,737	+		Rv3820c	0.23	+0.0
4,284,892	+		Rv3820c	0.34	+0.7
4,284,892	+		Rv3820c	0.34	+0.1
4,284,892	+		Rv3820c	0.34	+0.9
4,284,892	+		Rv3820c	0.34	-1.1
4,284,893	-		Rv3820c	0.34	+0.7
4,284,893	-		Rv3820c	0.34	+0.4
4,284,898	+		Rv3820c	0.34	+0.6
4,284,899	-		Rv3820c	0.34	-0.1
4,284,912	-		Rv3820c	0.35	+0.4
4,284,982	+		Rv3820c	0.40	+0.5
4,284,983	-		Rv3820c	0.40	+0.8
4,285,055	-		Rv3820c	0.45	+1.5
4,285,082	+		Rv3820c	0.47	+0.2
4,285,083	-		Rv3820c	0.47	+0.3
4,285,194	+		Rv3820c	0.55	+0.3
4,285,194	+		Rv3820c	0.55	+1.3
4,285,272	+		Rv3820c	0.61	+0.4
4,285,273	-		Rv3820c	0.61	-0.8
4,285,273	-		Rv3820c	0.61	-0.4
4,285,279	+		Rv3820c	0.61	+0.5
4,285,280	-		Rv3820c	0.61	+1.9
4,285,280	-		Rv3820c	0.61	-0.3