Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3716c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
4,159,594	-		Rv3714c	0.74	-0.2
4,159,600	+		Rv3714c	0.75	-0.3
4,159,601	-		Rv3714c	0.75	+0.3
4,159,679	+		Rv3714c	0.84	-0.2
4,159,679	+		Rv3714c	0.84	-0.8
4,159,680	-		Rv3714c	0.84	+1.9
4,159,680	-		Rv3714c	0.84	-0.2
4,159,680	-		Rv3714c	0.84	-0.2
4,159,680	-		Rv3714c	0.84	+0.8
4,160,029	-		Rv3715c	0.23	-0.0
4,160,193	+		Rv3715c	0.50	-0.2
4,160,399	+		Rv3715c	0.83	-0.1
4,160,572	-		Rv3716c	0.15	+0.7
4,161,000	+				-1.8
4,161,019	+				-3.1
4,161,019	+				-2.3
4,161,052	+				-1.5
4,161,052	+				-1.3
4,161,053	-				-1.6
4,161,491	-		Rv3717	0.61	-3.1
4,161,491	-		Rv3717	0.61	-1.8
4,161,567	+		Rv3717	0.71	-3.8
4,161,568	-		Rv3717	0.72	-1.8
4,161,568	-		Rv3717	0.72	-1.9
4,161,589	-		Rv3717	0.75	+0.3