Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3632

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
4,070,318	+		Rv3630	0.88	-0.4
4,070,409	+				+1.9
4,070,469	-				-1.4
4,070,499	-				-0.3
4,070,499	-				-0.9
4,070,511	+				+0.3
4,070,544	+				-0.9
4,070,704	+		Rv3631	0.26	-1.0
4,071,288	-		Rv3632	0.15	-0.5
4,071,341	+		Rv3632	0.30	-1.2
4,071,369	-		Rv3632	0.39	-1.9
4,071,369	-		Rv3632	0.39	-1.2
4,071,488	+		Rv3632	0.73	-0.6
4,071,488	+		Rv3632	0.73	+1.9
4,071,489	-		Rv3632	0.73	-0.5
4,071,489	-		Rv3632	0.73	-0.7
4,071,578	+				-0.1
4,071,668	-				-0.3
4,071,677	-				-0.2
4,071,682	+				-1.2
4,071,710	+				-0.6
4,071,710	+				-0.1
4,071,772	+				+0.5
4,071,846	-				-0.5
4,071,853	-				+0.1
4,071,891	-		Rv3633	0.11	+0.0
4,071,891	-		Rv3633	0.11	+0.5
4,071,894	+		Rv3633	0.12	-0.2
4,072,129	+		Rv3633	0.39	-0.1
4,072,129	+		Rv3633	0.39	-0.1
4,072,525	-		Rv3633	0.84	-1.1