Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3513c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
3,944,885	+				-0.1
3,944,885	+				-0.0
3,944,886	-				+0.1
3,944,961	+				-1.2
3,945,075	-				+0.1
3,945,564	+		Rv3513c	0.72	+1.0
3,945,564	+		Rv3513c	0.72	-2.4
3,945,564	+		Rv3513c	0.72	-0.0
3,945,686	-				-0.7
3,945,703	+				-1.4
3,945,703	+				-1.0
3,945,703	+				-0.3
3,945,703	+				-1.2
3,945,704	-				-0.7
3,945,704	-				-0.8
3,945,704	-				-0.3
3,945,704	-				+0.3
3,945,704	-				-0.5
3,945,706	+				-1.7
3,945,706	+				-0.0
3,945,706	+				-1.4
3,945,707	-				+0.5
3,945,707	-				-1.7
3,945,707	-				-0.4
3,945,721	+				+0.1
3,945,722	-				+0.4
3,945,734	+				-0.6
3,945,735	-				-0.5
3,945,735	-				+2.0