Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3306c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
3,691,860	+		Rv3305c	0.19	+0.1
3,691,963	+		Rv3305c	0.28	+0.7
3,692,694	+				+0.2
3,692,703	-				-1.4
3,692,727	-				-0.7
3,693,278	-		Rv3306c	0.40	+0.3
3,693,375	+		Rv3306c	0.48	-2.1
3,693,419	+		Rv3306c	0.52	+1.5
3,693,998	+				-0.9
3,694,040	+				-1.7
3,694,268	+		Rv3307	0.27	+1.9
3,694,349	-		Rv3307	0.37	-0.3
3,694,396	-		Rv3307	0.42	+0.4
3,694,396	-		Rv3307	0.42	-0.2
3,694,396	-		Rv3307	0.42	-0.1
3,694,532	-		Rv3307	0.59	-0.4
3,694,615	+		Rv3307	0.70	-0.8
3,694,615	+		Rv3307	0.70	-0.7
3,694,730	+		Rv3307	0.84	-0.2
3,694,858	+				+1.0