Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3230c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
3,606,389	-		Rv3229c	0.50	-0.4
3,606,640	+		Rv3229c	0.69	+0.8
3,606,641	-		Rv3229c	0.69	-0.1
3,606,641	-		Rv3229c	0.69	+1.2
3,606,911	-				+0.8
3,606,964	-				+0.3
3,607,068	-				-1.0
3,607,073	-				+0.3
3,607,113	+				+0.1
3,607,268	+		Rv3230c	0.14	+0.1
3,607,269	-		Rv3230c	0.14	+0.6
3,607,269	-		Rv3230c	0.14	+1.0
3,607,659	-		Rv3230c	0.48	+2.9
3,607,714	+		Rv3230c	0.53	+0.3
3,607,714	+		Rv3230c	0.53	+2.6
3,607,971	+		Rv3230c	0.75	-2.1
3,607,972	-		Rv3230c	0.75	+0.9
3,607,972	-		Rv3230c	0.75	-0.2
3,608,113	-		Rv3230c	0.88	+0.1
3,608,113	-		Rv3230c	0.88	+3.9
3,608,255	-				+0.5
3,608,255	-				-0.0
3,608,276	-				-0.9
3,608,320	+				+0.2
3,608,324	+				-0.0
3,608,531	-		Rv3231c	0.33	+0.1
3,608,531	-		Rv3231c	0.33	-0.9
3,608,602	+		Rv3231c	0.47	+0.2
3,608,603	-		Rv3231c	0.47	+0.1
3,608,603	-		Rv3231c	0.47	+0.4
3,608,755	+		Rv3231c	0.77	-0.1
3,608,756	-		Rv3231c	0.77	+0.2
3,608,860	+				-0.4
3,608,861	-				+0.9
3,608,895	+				+0.1
3,608,895	+				-0.3
3,608,896	-				-0.2
3,608,896	-				-0.0
3,608,896	-				-1.3
3,608,896	-				-0.1
3,608,907	+				-0.5
3,608,908	-				+1.0
3,608,908	-				+1.1
3,608,937	+				-0.9
3,608,937	+				-0.2
3,608,997	+		Rv3232c	0.14	-0.5
3,608,998	-		Rv3232c	0.14	-0.1
3,609,069	+		Rv3232c	0.22	-0.4
3,609,069	+		Rv3232c	0.22	-0.5
3,609,070	-		Rv3232c	0.23	-1.1
3,609,070	-		Rv3232c	0.23	-1.4
3,609,127	-		Rv3232c	0.29	+0.6