Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3204

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
3,580,324	-				+0.9
3,580,394	+				+0.4
3,580,493	+				+0.1
3,580,494	-				+0.2
3,580,545	+				+0.2
3,580,545	+				+0.3
3,580,683	-				-0.5
3,580,683	-				-0.2
3,580,805	+		Rv3203	0.25	-0.4
3,580,806	-		Rv3203	0.25	+0.7
3,581,166	+		Rv3203	0.78	-0.8
3,581,166	+		Rv3203	0.78	+0.7
3,581,206	+		Rv3203	0.84	-0.1
3,581,225	-		Rv3203	0.87	-0.2
3,581,227	+		Rv3203	0.87	-0.6
3,581,227	+		Rv3203	0.87	+0.2
3,581,394	-		Rv3204	0.26	-1.1
3,581,623	-				+0.1
3,582,494	-				-0.1
3,582,494	-				-0.2
3,582,513	+				-1.4
3,582,513	+				-0.5
3,582,525	-				-0.6
3,582,533	+				+0.6
3,582,534	-				-0.0
3,582,536	+				-0.1
3,582,536	+				+1.9
3,582,537	-				+0.2