Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3196A

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
3,565,845	+				-0.1
3,565,845	+				-0.5
3,565,845	+				+3.1
3,565,846	-				-1.3
3,565,876	+				-0.3
3,565,877	-				+0.0
3,565,877	-				+0.0
3,565,949	-		Rv3196	0.18	+0.6
3,566,092	+		Rv3196	0.34	+0.1
3,566,092	+		Rv3196	0.34	+0.9
3,566,092	+		Rv3196	0.34	+0.8
3,566,093	-		Rv3196	0.34	+0.3
3,566,093	-		Rv3196	0.34	+0.4
3,566,093	-		Rv3196	0.34	-1.0
3,566,286	+		Rv3196	0.55	+1.3
3,566,286	+		Rv3196	0.55	+0.0
3,566,286	+		Rv3196	0.55	+1.1
3,566,287	-		Rv3196	0.55	-0.4
3,566,643	-				+0.2
3,566,691	+				+0.4
3,566,692	-				+0.8
3,566,692	-				+0.2
3,566,698	-				+0.2
3,566,698	-				+0.2
3,566,742	+		Rv3196A	0.23	-2.3
3,566,743	-		Rv3196A	0.23	-1.2
3,566,743	-		Rv3196A	0.23	-0.2
3,567,146	+				-0.2
3,567,147	-				-1.3
3,567,684	+		Rv3197	0.49	-0.2
3,567,684	+		Rv3197	0.49	-0.1
3,567,685	-		Rv3197	0.49	+0.3
3,567,822	-		Rv3197	0.59	+1.9