Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3170

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
3,537,850	+		Rv3169	0.54	-0.3
3,537,850	+		Rv3169	0.54	-0.6
3,537,850	+		Rv3169	0.54	-0.9
3,537,851	-		Rv3169	0.54	-1.3
3,537,851	-		Rv3169	0.54	-0.4
3,538,180	+		Rv3169	0.84	-0.2
3,538,251	-				-0.3
3,538,347	+				-0.0
3,538,376	-				-0.0
3,538,395	+				-0.2
3,538,466	+				-0.0
3,538,499	-				-0.5
3,539,070	-		Rv3170	0.42	-1.8
3,539,073	+		Rv3170	0.42	-1.0
3,539,073	+		Rv3170	0.42	-0.8
3,539,074	-		Rv3170	0.42	-0.2
3,539,789	+				+0.1
3,539,847	+				-1.4
3,540,036	-		Rv3171c	0.21	+1.2
3,540,540	+		Rv3171c	0.77	-0.3
3,540,762	-				-0.6