Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3140

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
3,505,825	-		Rv3139	0.33	-0.9
3,505,825	-		Rv3139	0.33	-0.8
3,505,857	+		Rv3139	0.35	+2.9
3,505,913	-		Rv3139	0.39	+0.8
3,506,178	+		Rv3139	0.58	-1.1
3,506,179	-		Rv3139	0.58	-1.0
3,506,440	+		Rv3139	0.77	-0.7
3,506,689	+				-1.8
3,506,690	-				-0.9
3,506,907	+				-1.7
3,507,046	+		Rv3140	0.21	-0.6
3,507,357	-		Rv3140	0.47	-2.2
3,507,357	-		Rv3140	0.47	-1.2
3,507,612	-		Rv3140	0.68	-1.2
3,507,646	-		Rv3140	0.71	-1.2
3,508,225	+		Rv3141	0.13	-0.2
3,508,246	-		Rv3141	0.16	-0.4
3,508,470	+		Rv3141	0.39	+1.9
3,508,471	-		Rv3141	0.39	-0.4
3,508,723	+		Rv3141	0.65	+0.2
3,508,871	-		Rv3141	0.80	-0.4
3,508,943	-		Rv3141	0.87	+0.4
3,508,943	-		Rv3141	0.87	-0.4
3,508,980	+				+0.2