Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3102c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3100c and Rv3101c are separated by 2 nucleotidesRv3101c and Rv3102c are separated by 0 nucleotidesRv3102c and Rv3103c are separated by 43 nucleotidesRv3103c and Rv3104c are separated by 1 nucleotides Rv3100c: Rv3100c - Probable SSRA-binding protein SmpB, at 3,469,301 to 3,469,783 Rv3100c Rv3101c: Rv3101c - Putative cell division protein FtsX (septation component-transport integral membrane protein ABC transporter), at 3,469,786 to 3,470,679 Rv3101c Rv3102c: Rv3102c - Putative cell division ATP-binding protein FtsE (septation component-transport ATP-binding protein ABC transporter), at 3,470,680 to 3,471,369 Rv3102c Rv3103c: Rv3103c - Hypothetical proline-rich protein, at 3,471,413 to 3,471,850 Rv3103c Rv3104c: Rv3104c - Possible conserved transmembrane protein, at 3,471,852 to 3,472,778 Rv3104c Position (kb) 3470 3471 3472Strain fitness (log2 ratio) -5 -4 -3 -2 -1 0 1at 3469.788 kb on - strandat 3469.814 kb on - strandat 3470.373 kb on - strand, within Rv3101cat 3470.566 kb on - strand, within Rv3101cat 3470.660 kb on - strandat 3470.831 kb on - strand, within Rv3102cat 3470.848 kb on - strand, within Rv3102cat 3471.078 kb on - strand, within Rv3102cat 3471.385 kb on + strandat 3471.441 kb on + strandat 3471.442 kb on - strandat 3471.657 kb on + strand, within Rv3103cat 3471.657 kb on + strand, within Rv3103cat 3471.658 kb on - strand, within Rv3103cat 3471.733 kb on + strand, within Rv3103cat 3471.735 kb on + strand, within Rv3103cat 3471.735 kb on + strand, within Rv3103cat 3471.735 kb on + strand, within Rv3103cat 3471.736 kb on - strand, within Rv3103cat 3471.736 kb on - strand, within Rv3103cat 3471.736 kb on - strand, within Rv3103cat 3471.745 kb on - strand, within Rv3103cat 3471.745 kb on - strand, within Rv3103c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL
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3,469,788 - +1.1
3,469,814 - -4.8
3,470,373 - Rv3101c 0.66 -1.3
3,470,566 - Rv3101c 0.87 -4.0
3,470,660 - -3.5
3,470,831 - Rv3102c 0.22 -2.7
3,470,848 - Rv3102c 0.24 -4.4
3,471,078 - Rv3102c 0.58 -3.4
3,471,385 + -0.1
3,471,441 + -0.7
3,471,442 - +0.9
3,471,657 + Rv3103c 0.56 +0.4
3,471,657 + Rv3103c 0.56 -0.2
3,471,658 - Rv3103c 0.56 +0.4
3,471,733 + Rv3103c 0.73 -1.8
3,471,735 + Rv3103c 0.74 -0.3
3,471,735 + Rv3103c 0.74 -0.6
3,471,735 + Rv3103c 0.74 -0.4
3,471,736 - Rv3103c 0.74 -0.4
3,471,736 - Rv3103c 0.74 +0.1
3,471,736 - Rv3103c 0.74 -0.1
3,471,745 - Rv3103c 0.76 -1.3
3,471,745 - Rv3103c 0.76 -0.1

Or see this region's nucleotide sequence