Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2989

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
3,346,159	-				-1.0
3,346,513	-		Rv2989	0.52	-3.5
3,346,860	+				+1.6
3,346,861	-				-0.3
3,346,884	+				-0.4
3,346,884	+				-0.3
3,346,884	+				+2.9
3,346,885	-				+0.0
3,346,885	-				+0.7
3,346,956	+		Rv2990c	0.11	-0.0
3,347,232	+		Rv2990c	0.43	-0.2
3,347,233	-		Rv2990c	0.43	-1.0
3,347,233	-		Rv2990c	0.43	-0.4
3,347,233	-		Rv2990c	0.43	-1.1
3,347,233	-		Rv2990c	0.43	-0.1
3,347,250	-		Rv2990c	0.45	+0.3
3,347,253	+		Rv2990c	0.46	+0.2
3,347,253	+		Rv2990c	0.46	+0.0
3,347,253	+		Rv2990c	0.46	+0.5
3,347,253	+		Rv2990c	0.46	-0.5
3,347,314	-		Rv2990c	0.53	+0.7
3,347,347	-		Rv2990c	0.57	-0.6
3,347,396	+		Rv2990c	0.62	+0.4
3,347,441	-		Rv2990c	0.68	-0.3
3,347,631	-		Rv2990c	0.90	+0.3
3,347,631	-		Rv2990c	0.90	-0.3
3,347,631	-		Rv2990c	0.90	-0.3
3,347,634	+				-0.0
3,347,634	+				-0.1
3,347,635	-				+0.7
3,347,635	-				-1.2
3,347,657	+				+0.1
3,347,658	-				-1.1
3,347,658	-				-1.3
3,347,658	-				-1.0
3,347,658	-				-0.3
3,347,818	-				+0.1