Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2817c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv2816c and Rv2817c are separated by 0 nucleotidesRv2817c and Rv2818c are separated by 12 nucleotides Rv2816c: Rv2816c - Conserved hypothetical protein, at 3,123,625 to 3,123,966 Rv2816c Rv2817c: Rv2817c - Conserved hypothetical protein, at 3,123,967 to 3,124,983 Rv2817c Rv2818c: Rv2818c - Hypothetical protein, at 3,124,996 to 3,126,144 Rv2818c Position (kb) 3123 3124 3125Strain fitness (log2 ratio) -1 0 1 2 3at 3123.877 kb on + strand, within Rv2816cat 3123.898 kb on + strand, within Rv2816cat 3123.941 kb on + strandat 3123.968 kb on + strandat 3124.247 kb on - strand, within Rv2817cat 3124.276 kb on + strand, within Rv2817cat 3124.385 kb on + strand, within Rv2817cat 3124.970 kb on + strandat 3124.971 kb on - strandat 3125.051 kb on + strandat 3125.052 kb on - strandat 3125.372 kb on + strand, within Rv2818cat 3125.419 kb on - strand, within Rv2818cat 3125.663 kb on + strand, within Rv2818c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL
remove
3,123,877 + Rv2816c 0.74 -0.1
3,123,898 + Rv2816c 0.80 +0.5
3,123,941 + -0.1
3,123,968 + -0.1
3,124,247 - Rv2817c 0.28 +3.7
3,124,276 + Rv2817c 0.30 +1.2
3,124,385 + Rv2817c 0.41 -0.3
3,124,970 + -1.7
3,124,971 - -0.6
3,125,051 + +0.7
3,125,052 - +1.9
3,125,372 + Rv2818c 0.33 -0.1
3,125,419 - Rv2818c 0.37 -0.8
3,125,663 + Rv2818c 0.58 +0.1

Or see this region's nucleotide sequence