Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2630

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
2,956,014	+		Rv2629	0.22	-0.3
2,956,079	+		Rv2629	0.28	-0.2
2,956,080	-		Rv2629	0.28	-0.3
2,956,096	-		Rv2629	0.29	-0.5
2,956,096	-		Rv2629	0.29	-0.8
2,956,125	+		Rv2629	0.32	-0.5
2,956,125	+		Rv2629	0.32	-1.6
2,956,126	-		Rv2629	0.32	+0.1
2,956,166	+		Rv2629	0.35	-0.2
2,956,514	+		Rv2629	0.66	-0.3
2,956,687	+		Rv2629	0.82	-0.7
2,956,828	-				+1.1
2,956,853	+				-0.7
2,956,853	+				-0.6
2,956,882	+				-0.1
2,956,883	-				-0.2
2,957,203	+		Rv2630	0.57	+0.3
2,957,332	+		Rv2630	0.81	-1.8
2,957,333	-		Rv2630	0.81	+1.9
2,957,621	-				+1.9
2,957,727	+		Rv2631	0.12	-0.4
2,957,727	+		Rv2631	0.12	+0.4
2,957,741	+		Rv2631	0.13	-0.2
2,957,742	-		Rv2631	0.13	-0.1
2,957,742	-		Rv2631	0.13	-0.9
2,958,088	+		Rv2631	0.40	-0.1
2,958,089	-		Rv2631	0.40	+1.9
2,958,320	-		Rv2631	0.58	-0.3