Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2170

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
2,431,567	-				-0.2
2,431,711	-		Rv2169c	0.36	-1.1
2,432,003	-				-1.1
2,432,051	-				+0.1
2,432,051	-				+0.4
2,432,051	-				+0.2
2,432,071	-				-0.9
2,432,136	+				+0.7
2,432,142	-				+0.9
2,432,142	-				-0.2
2,432,242	+				-1.1
2,432,243	-				-0.5
2,432,304	+		Rv2170	0.11	-0.9
2,432,305	-		Rv2170	0.11	-1.3
2,432,917	+				-2.2
2,432,917	+				-0.4
2,432,921	+				-0.4
2,432,921	+				+0.9
2,432,922	-				-2.8
2,433,188	+		Rv2171	0.35	-2.0
2,433,188	+		Rv2171	0.35	-1.6
2,433,188	+		Rv2171	0.35	-0.4
2,433,427	-		Rv2171	0.70	-1.0