Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2072c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
2,328,232	+				-0.2
2,328,233	-				-0.1
2,328,258	+				-0.7
2,328,258	+				+0.4
2,328,259	-				-0.3
2,328,262	+				-1.8
2,328,262	+				-0.3
2,328,263	-				-0.2
2,328,263	-				-1.7
2,328,883	+		Rv2071c	0.87	+0.6
2,328,933	+				-0.3
2,328,933	+				-0.3
2,328,934	-				-0.4
2,328,934	-				-0.2
2,328,967	+				-0.5
2,328,967	+				-0.4
2,328,968	-				-0.1
2,329,540	-		Rv2072c	0.48	+0.9
2,329,943	+		Rv2072c	0.83	-0.2
2,330,307	-		Rv2073c	0.12	-0.1
2,330,506	+		Rv2073c	0.39	-0.6
2,330,506	+		Rv2073c	0.39	+0.0
2,330,506	+		Rv2073c	0.39	+0.9
2,330,506	+		Rv2073c	0.39	-1.4
2,330,507	-		Rv2073c	0.39	+0.6
2,330,507	-		Rv2073c	0.39	-1.1
2,330,507	-		Rv2073c	0.39	-0.4
2,330,507	-		Rv2073c	0.39	-0.3
2,330,507	-		Rv2073c	0.39	-0.4
2,330,507	-		Rv2073c	0.39	-1.4
2,330,507	-		Rv2073c	0.39	-0.3
2,330,620	+		Rv2073c	0.54	+0.0
2,330,799	+		Rv2073c	0.78	+0.2
2,330,799	+		Rv2073c	0.78	-0.6
2,330,801	+		Rv2073c	0.78	+0.4
2,330,935	-				-1.2
2,330,937	+				-0.0
2,330,973	+				-0.4
2,330,974	-				-0.4
2,331,013	+				+0.6
2,331,013	+				+0.0
2,331,014	-				-0.3