Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2009

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
2,257,282	-		Rv2008c	0.50	-0.1
2,257,337	+		Rv2008c	0.54	-0.5
2,257,481	-		Rv2008c	0.65	+0.1
2,257,590	-		Rv2008c	0.73	-0.7
2,257,739	+		Rv2008c	0.85	-0.2
2,257,865	+				-0.1
2,257,866	-				-0.3
2,258,008	+				+0.9
2,258,008	+				+0.5
2,258,008	+				+0.6
2,258,008	+				+1.9
2,258,008	+				+0.2
2,258,009	-				-0.2
2,258,102	+		Rv2009	0.30	-2.6
2,258,103	-		Rv2009	0.30	-0.9
2,258,270	+				-0.3
2,258,271	-				-0.2
2,258,271	-				+0.9
2,258,303	+				+0.1
2,258,544	+		Rv2010	0.68	+1.5
2,258,545	-		Rv2010	0.68	-0.1
2,258,545	-		Rv2010	0.68	-0.8
2,258,738	-				+0.4
2,258,747	+				-0.8
2,258,790	-				-0.3
2,259,229	+		Rv2011c	0.87	-0.2
2,259,230	-		Rv2011c	0.87	-0.2
2,259,230	-		Rv2011c	0.87	-0.4
2,259,250	+				-0.4