Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2001

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
2,245,845	+		Rv2000	0.39	+0.3
2,245,845	+		Rv2000	0.39	-0.1
2,245,845	+		Rv2000	0.39	-0.2
2,245,845	+		Rv2000	0.39	+0.4
2,245,846	-		Rv2000	0.39	+0.0
2,245,953	+		Rv2000	0.46	+0.4
2,245,954	-		Rv2000	0.46	+2.5
2,245,954	-		Rv2000	0.46	-0.8
2,245,996	+		Rv2000	0.49	-0.1
2,245,996	+		Rv2000	0.49	-0.4
2,245,997	-		Rv2000	0.49	+0.0
2,245,997	-		Rv2000	0.49	-0.0
2,246,235	+		Rv2000	0.64	-0.1
2,246,236	-		Rv2000	0.64	+1.0
2,246,379	+		Rv2000	0.72	+0.0
2,246,379	+		Rv2000	0.72	-0.3
2,246,379	+		Rv2000	0.72	-0.7
2,246,382	-		Rv2000	0.73	-0.6
2,246,446	+		Rv2000	0.77	-0.4
2,246,447	-		Rv2000	0.77	+0.0
2,246,549	+		Rv2000	0.83	-0.5
2,246,608	+		Rv2000	0.87	+0.2
2,246,630	-		Rv2000	0.88	+0.2
2,246,776	+				-0.1
2,246,893	-				-0.0
2,246,893	-				-0.3
2,247,409	+		Rv2001	0.77	-1.9
2,247,410	-		Rv2001	0.77	-1.4
2,247,580	+				-0.7
2,247,580	+				+0.1
2,247,713	+				-0.1
2,248,376	-				-0.1
2,248,440	+				+1.9
2,248,565	-				-1.2