Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1986

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
2,229,103	+		Rv1985c	0.12	-0.1
2,229,123	+		Rv1985c	0.14	+0.1
2,229,123	+		Rv1985c	0.14	-0.2
2,229,124	-		Rv1985c	0.15	+0.6
2,229,405	+		Rv1985c	0.45	+0.9
2,229,406	-		Rv1985c	0.46	+0.4
2,229,406	-		Rv1985c	0.46	+0.9
2,229,406	-		Rv1985c	0.46	-0.2
2,229,601	-		Rv1985c	0.67	-0.1
2,229,707	+		Rv1985c	0.79	-0.2
2,229,708	-		Rv1985c	0.79	+0.0
2,229,708	-		Rv1985c	0.79	-1.1
2,229,708	-		Rv1985c	0.79	+0.1
2,229,813	+				-1.7
2,229,814	-				-0.4
2,229,814	-				-1.1
2,229,814	-				-1.0
2,230,384	-		Rv1986	0.62	-0.2
2,230,384	-		Rv1986	0.62	-1.9
2,230,478	-		Rv1986	0.78	-0.7
2,230,608	+				-0.5
2,230,611	+				-0.1
2,230,611	+				-0.2
2,230,612	-				-1.3
2,230,612	-				-0.3
2,230,662	+				-0.3
2,230,662	+				-0.1
2,230,663	-				-1.0
2,230,663	-				-0.0
2,230,783	-				-0.5
2,230,803	-				-0.1
2,230,839	+				-0.0
2,231,013	-				+0.8
2,231,044	+				-0.7
2,231,045	-				-1.4
2,231,045	-				-1.7
2,231,093	+		Rv1987	0.16	-0.6
2,231,093	+		Rv1987	0.16	-0.2
2,231,094	-		Rv1987	0.16	-1.4
2,231,290	-		Rv1987	0.62	-0.8
2,231,290	-		Rv1987	0.62	-0.9
2,231,290	-		Rv1987	0.62	+0.3
2,231,317	+		Rv1987	0.68	-0.2
2,231,317	+		Rv1987	0.68	-0.8
2,231,318	-		Rv1987	0.68	+2.9
2,231,318	-		Rv1987	0.68	-0.3
2,231,381	+		Rv1987	0.83	-0.4
2,231,404	+		Rv1987	0.88	-0.4
2,231,440	+				+0.6
2,231,440	+				-1.2
2,231,497	+				-1.8
2,231,514	-				-1.7
2,231,514	-				-0.5