Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1906c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
2,151,510	-				+0.5
2,151,625	+		Rv1905c	0.20	+1.1
2,151,625	+		Rv1905c	0.20	-0.4
2,151,626	-		Rv1905c	0.20	+0.6
2,151,626	-		Rv1905c	0.20	-0.2
2,151,626	-		Rv1905c	0.20	+0.7
2,151,626	-		Rv1905c	0.20	-0.6
2,151,626	-		Rv1905c	0.20	+0.7
2,151,659	-		Rv1905c	0.23	+1.9
2,151,696	+		Rv1905c	0.27	-0.2
2,151,697	-		Rv1905c	0.27	+0.4
2,151,697	-		Rv1905c	0.27	+1.9
2,151,716	-		Rv1905c	0.29	-0.5
2,151,716	-		Rv1905c	0.29	+0.9
2,151,738	-		Rv1905c	0.32	-1.3
2,151,883	+		Rv1905c	0.47	-0.4
2,151,883	+		Rv1905c	0.47	-0.1
2,151,884	-		Rv1905c	0.47	-0.1
2,151,920	-		Rv1905c	0.51	-0.6
2,151,990	+		Rv1905c	0.58	-0.1
2,151,990	+		Rv1905c	0.58	+0.0
2,151,990	+		Rv1905c	0.58	-0.2
2,152,110	+		Rv1905c	0.70	-0.1
2,152,210	+		Rv1905c	0.81	-0.0
2,152,211	-		Rv1905c	0.81	-1.9
2,152,330	+				+2.5
2,152,330	+				-0.4
2,152,331	-				+1.5
2,152,387	+				-0.7
2,152,387	+				-1.2
2,152,388	-				-0.8
2,152,388	-				-0.5
2,152,388	-				+0.4
2,152,388	-				-1.3
2,152,491	+		Rv1906c	0.14	-1.1
2,152,491	+		Rv1906c	0.14	-1.5
2,152,492	-		Rv1906c	0.14	-0.1
2,152,492	-		Rv1906c	0.14	-1.9
2,152,612	-		Rv1906c	0.40	-0.9
2,152,678	+		Rv1906c	0.54	-0.8
2,152,748	-		Rv1906c	0.69	-0.7
2,152,748	-		Rv1906c	0.69	-0.8
2,152,903	+				-0.6
2,152,903	+				-1.0
2,152,903	+				-0.9
2,152,904	-				-2.3
2,152,909	-				-0.3
2,152,994	+				-0.1
2,152,994	+				+0.0
2,153,125	+				-0.9
2,153,386	+		Rv1907c	0.23	+0.1
2,153,387	-		Rv1907c	0.23	+1.9
2,153,408	+		Rv1907c	0.27	+0.1
2,153,409	-		Rv1907c	0.27	-0.8
2,153,619	+		Rv1907c	0.59	+0.4
2,153,665	+		Rv1907c	0.66	+0.5
2,153,665	+		Rv1907c	0.66	-1.3
2,153,666	-		Rv1907c	0.67	-0.1