Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1897c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
2,143,524	+		Rv1895	0.87	+0.0
2,143,524	+		Rv1895	0.87	-0.2
2,143,525	-		Rv1895	0.87	-0.7
2,143,558	-				-1.0
2,143,587	-				-0.6
2,143,673	+				-0.4
2,143,704	+		Rv1896c	0.19	+1.2
2,143,738	+		Rv1896c	0.22	-0.2
2,143,738	+		Rv1896c	0.22	-1.1
2,143,738	+		Rv1896c	0.22	-0.5
2,143,885	-		Rv1896c	0.38	-0.4
2,144,025	-		Rv1896c	0.54	-0.8
2,144,025	-		Rv1896c	0.54	+0.8
2,144,103	+		Rv1896c	0.62	-0.5
2,144,147	+		Rv1896c	0.67	+0.1
2,144,205	+		Rv1896c	0.73	-0.9
2,144,253	-		Rv1896c	0.79	+1.9
2,144,440	+				-1.1
2,144,441	-				-2.0
2,144,644	+		Rv1897c	0.45	+0.2
2,144,645	-		Rv1897c	0.45	+1.0
2,144,645	-		Rv1897c	0.45	-0.2
2,144,664	+		Rv1897c	0.49	+1.1
2,144,907	+				-0.3
2,144,928	+				+0.0
2,144,928	+				-0.1
2,145,083	+		Rv1898	0.46	-0.5
2,145,228	+				+0.5
2,145,246	+				-0.3
2,145,247	-				+2.9
2,145,247	-				+0.2
2,145,292	+				+0.4
2,145,292	+				-0.4
2,145,293	-				+0.2
2,145,293	-				-0.1
2,145,487	+		Rv1899c	0.26	+0.5
2,145,487	+		Rv1899c	0.26	-0.4
2,145,488	-		Rv1899c	0.27	-0.1
2,145,488	-		Rv1899c	0.27	-1.3
2,145,712	+		Rv1899c	0.48	+0.0
2,145,712	+		Rv1899c	0.48	-0.5
2,145,713	-		Rv1899c	0.48	+0.1
2,145,713	-		Rv1899c	0.48	+0.3
2,145,713	-		Rv1899c	0.48	+0.7
2,145,713	-		Rv1899c	0.48	-0.2
2,145,753	+		Rv1899c	0.52	+0.9
2,145,754	-		Rv1899c	0.52	+0.3