Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1885c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
2,133,325	+		Rv1883c	0.20	+0.0
2,133,325	+		Rv1883c	0.20	-0.3
2,133,325	+		Rv1883c	0.20	-0.2
2,133,326	-		Rv1883c	0.21	-1.1
2,133,326	-		Rv1883c	0.21	+0.2
2,133,328	+		Rv1883c	0.21	-0.2
2,133,329	-		Rv1883c	0.21	-1.3
2,133,329	-		Rv1883c	0.21	+0.1
2,133,406	+		Rv1883c	0.38	-0.3
2,133,474	+		Rv1883c	0.53	-0.7
2,133,474	+		Rv1883c	0.53	-0.2
2,133,692	+				+0.1
2,133,692	+				+0.4
2,133,693	-				-0.1
2,133,693	-				+1.4
2,133,708	+				+0.2
2,134,193	+		Rv1884c	0.87	+0.3
2,134,298	+				-0.3
2,134,339	-		Rv1885c	0.11	+0.4
2,134,449	+		Rv1885c	0.29	+0.7
2,134,483	+		Rv1885c	0.35	+0.3
2,134,483	+		Rv1885c	0.35	-0.2
2,134,484	-		Rv1885c	0.35	+0.0
2,134,544	+		Rv1885c	0.45	-0.1
2,134,596	-		Rv1885c	0.54	-0.2
2,134,796	-		Rv1885c	0.87	-0.1
2,134,847	+				+1.9
2,134,849	+				-0.1
2,134,849	+				+0.7
2,134,849	+				+0.0
2,134,850	-				+0.7
2,134,850	-				-0.7
2,134,850	-				-0.6
2,134,850	-				+0.1
2,134,850	-				+1.9
2,134,850	-				-0.4
2,134,952	-				-0.1
2,135,017	+		Rv1886c	0.13	-0.2
2,135,017	+		Rv1886c	0.13	-0.6
2,135,017	+		Rv1886c	0.13	-0.8
2,135,017	+		Rv1886c	0.13	-0.3
2,135,017	+		Rv1886c	0.13	-0.3
2,135,018	-		Rv1886c	0.13	+0.2
2,135,018	-		Rv1886c	0.13	-0.2
2,135,018	-		Rv1886c	0.13	+0.4
2,135,018	-		Rv1886c	0.13	-0.3
2,135,076	+		Rv1886c	0.19	-1.5
2,135,076	+		Rv1886c	0.19	-2.0
2,135,076	+		Rv1886c	0.19	-0.4
2,135,077	-		Rv1886c	0.19	-0.3
2,135,077	-		Rv1886c	0.19	-0.2
2,135,077	-		Rv1886c	0.19	-0.0
2,135,168	+		Rv1886c	0.28	+0.3
2,135,169	-		Rv1886c	0.29	-0.5
2,135,264	+		Rv1886c	0.38	-0.2
2,135,314	+		Rv1886c	0.43	-0.3
2,135,464	+		Rv1886c	0.59	-0.5
2,135,464	+		Rv1886c	0.59	-0.7
2,135,464	+		Rv1886c	0.59	-1.2
2,135,464	+		Rv1886c	0.59	-0.5
2,135,464	+		Rv1886c	0.59	+0.9
2,135,465	-		Rv1886c	0.59	-0.4
2,135,465	-		Rv1886c	0.59	-0.2
2,135,500	+		Rv1886c	0.62	-0.9
2,135,501	-		Rv1886c	0.62	-0.0
2,135,545	-		Rv1886c	0.67	-2.0
2,135,563	+		Rv1886c	0.69	-0.5
2,135,564	-		Rv1886c	0.69	-0.5
2,135,567	-		Rv1886c	0.69	+0.9
2,135,591	+		Rv1886c	0.72	-0.8
2,135,605	+		Rv1886c	0.73	-0.3
2,135,605	+		Rv1886c	0.73	+0.2
2,135,606	-		Rv1886c	0.73	-1.5
2,135,639	-		Rv1886c	0.77	-1.3
2,135,719	+		Rv1886c	0.85	-0.2
2,135,799	+				-0.1
2,135,799	+				+0.1
2,135,799	+				-1.3
2,135,867	+				-0.2
2,135,867	+				+0.2
2,135,867	+				+0.2
2,135,867	+				-0.7
2,135,868	-				+0.3
2,135,868	-				-0.6