Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1870c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
2,119,832	+		Rv1869c	0.30	-0.9
2,119,869	+		Rv1869c	0.33	+1.3
2,119,869	+		Rv1869c	0.33	+0.1
2,119,869	+		Rv1869c	0.33	-0.1
2,119,870	-		Rv1869c	0.33	+0.1
2,120,081	+		Rv1869c	0.50	+0.8
2,120,082	-		Rv1869c	0.50	+1.3
2,120,082	-		Rv1869c	0.50	+0.9
2,120,106	-		Rv1869c	0.52	-1.1
2,120,339	+		Rv1869c	0.71	+1.8
2,120,388	+		Rv1869c	0.75	+0.1
2,120,696	-				-0.1
2,120,696	-				+0.3
2,120,696	-				-1.1
2,120,696	-				+0.9
2,120,796	+				-0.2
2,120,811	-				+0.2
2,120,920	-		Rv1870c	0.20	-0.5
2,121,008	-		Rv1870c	0.33	-2.3
2,121,008	-		Rv1870c	0.33	-0.1
2,121,070	-		Rv1870c	0.43	-0.1
2,121,127	-		Rv1870c	0.52	-0.2
2,121,136	-		Rv1870c	0.54	+0.4
2,121,136	-		Rv1870c	0.54	+0.3
2,121,342	+		Rv1870c	0.86	+0.6
2,121,342	+		Rv1870c	0.86	-0.3
2,121,342	+		Rv1870c	0.86	-0.5
2,121,343	-		Rv1870c	0.86	+0.1
2,121,343	-		Rv1870c	0.86	-0.6
2,121,361	+		Rv1870c	0.89	-0.0
2,121,361	+		Rv1870c	0.89	-0.9
2,121,362	-		Rv1870c	0.89	-0.5
2,121,410	-				-1.6
2,121,439	+				-1.2
2,121,439	+				-1.0
2,121,469	+				-0.3
2,121,544	-		Rv1871c	0.13	-1.0
2,121,568	-		Rv1871c	0.19	+0.2
2,121,610	+		Rv1871c	0.29	-0.2
2,121,611	-		Rv1871c	0.30	-0.3
2,121,676	+		Rv1871c	0.46	+0.9
2,121,676	+		Rv1871c	0.46	+0.3
2,121,676	+		Rv1871c	0.46	+1.2
2,121,676	+		Rv1871c	0.46	-1.6
2,121,682	+		Rv1871c	0.48	-0.1
2,121,682	+		Rv1871c	0.48	-0.9
2,121,683	-		Rv1871c	0.48	-0.8
2,121,730	-		Rv1871c	0.60	-0.5
2,121,872	+				-0.9
2,121,873	-				-0.5
2,121,873	-				-0.6
2,121,873	-				-0.2
2,122,079	+		Rv1872c	0.14	-0.3