Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1657

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1655 and Rv1656 overlap by 4 nucleotidesRv1656 and Rv1657 overlap by 4 nucleotidesRv1657 and Rv1658 are separated by 8 nucleotides Rv1655: Rv1655 - Probable acetylornithine aminotransferase ArgD, at 1,868,723 to 1,869,925 Rv1655 Rv1656: Rv1656 - Probable ornithine carbamoyltransferase, anabolic ArgF, at 1,869,922 to 1,870,845 Rv1656 Rv1657: Rv1657 - Probable arginine repressor ArgR (AHRC), at 1,870,842 to 1,871,354 Rv1657 Rv1658: Rv1658 - Probable argininosuccinate synthase ArgG, at 1,871,363 to 1,872,559 Rv1658 Position (kb) 1870 1871 1872Strain fitness (log2 ratio) -1 0 1at 1871.073 kb on + strand, within Rv1657at 1871.217 kb on + strand, within Rv1657at 1871.218 kb on - strand, within Rv1657

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL
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1,871,073 + Rv1657 0.45 +0.1
1,871,217 + Rv1657 0.73 -1.0
1,871,218 - Rv1657 0.73 -1.5

Or see this region's nucleotide sequence