Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1637c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,841,899	+		Rv1635c	0.79	+1.0
1,841,922	-		Rv1635c	0.81	-0.2
1,841,940	+		Rv1635c	0.82	-1.2
1,841,940	+		Rv1635c	0.82	-1.1
1,841,940	+		Rv1635c	0.82	+1.9
1,841,941	-		Rv1635c	0.82	+0.3
1,841,941	-		Rv1635c	0.82	-0.6
1,842,155	+				+1.9
1,842,387	+				-0.5
1,842,391	+				+0.5
1,842,391	+				+0.3
1,842,391	+				-0.5
1,842,391	+				+0.1
1,842,426	+				+0.0
1,842,426	+				+1.1
1,842,890	-				-0.7
1,842,899	+				+0.2
1,842,974	+				-0.0
1,842,975	-				+0.1
1,842,975	-				+0.3
1,842,995	+		Rv1637c	0.12	-0.3
1,842,996	-		Rv1637c	0.12	+0.3
1,843,371	-		Rv1637c	0.59	-0.3
1,843,553	+		Rv1637c	0.82	+0.3
1,843,554	-		Rv1637c	0.83	+1.2
1,843,554	-		Rv1637c	0.83	+0.7
1,843,576	-		Rv1637c	0.85	-0.3
1,843,632	+				-0.9
1,843,645	+				+1.9
1,843,687	+				-1.0
1,843,687	+				-0.1
1,843,687	+				+0.6
1,843,688	-				-0.1
1,843,688	-				-0.6
1,843,688	-				-0.9
1,843,900	+				-0.3
1,843,922	-				-0.5
1,844,056	+		Rv1638	0.11	-0.9
1,844,077	+		Rv1638	0.12	-0.5
1,844,245	-		Rv1638	0.17	-1.9