Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1624c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,825,940	+				-2.5
1,825,941	-				-0.8
1,825,943	+				-2.7
1,826,094	+		Rv1624c	0.16	+0.3
1,826,094	+		Rv1624c	0.16	+1.2
1,826,198	+		Rv1624c	0.34	-0.1
1,826,198	+		Rv1624c	0.34	-0.9
1,826,410	+		Rv1624c	0.70	+0.8
1,826,410	+		Rv1624c	0.70	-0.8
1,826,446	-		Rv1624c	0.76	+0.4
1,826,587	+				-0.7
1,826,587	+				-0.3
1,826,587	+				-0.2
1,826,687	+				+0.9
1,826,688	-				-0.1
1,826,688	-				-0.9
1,826,688	-				+0.2
1,826,701	+				-0.4
1,826,701	+				-0.6
1,826,702	-				-1.7
1,826,722	+				+0.1
1,826,722	+				-0.1
1,826,722	+				-0.4
1,826,723	-				-0.1
1,826,723	-				-0.2
1,826,723	-				+0.1
1,826,723	-				-0.4
1,826,723	-				+0.9
1,826,723	-				+1.8
1,827,000	+		Rv1625c	0.29	-0.7
1,827,042	-		Rv1625c	0.32	+1.3
1,827,042	-		Rv1625c	0.32	-0.9
1,827,042	-		Rv1625c	0.32	+1.9
1,827,107	+		Rv1625c	0.37	-0.6
1,827,108	-		Rv1625c	0.37	+0.0
1,827,150	+		Rv1625c	0.40	-0.5
1,827,151	-		Rv1625c	0.40	+0.9
1,827,207	-		Rv1625c	0.45	-0.3
1,827,241	-		Rv1625c	0.47	+3.5
1,827,241	-		Rv1625c	0.47	+0.1
1,827,368	-		Rv1625c	0.57	+0.2
1,827,404	-		Rv1625c	0.59	-0.4
1,827,404	-		Rv1625c	0.59	+0.3
1,827,550	+		Rv1625c	0.70	+0.3