Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1421
Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.
Per-strain Table
| Position | Strand | Gene | LocusTag | Fraction | 7H9 with Bedaquiline 0.15 ug/mL |
|---|---|---|---|---|---|
| remove | |||||
| 1,595,759 | - | Rv1420 | 0.88 | -0.2 | |
| 1,596,105 | + | Rv1421 | 0.14 | -0.7 | |
| 1,596,400 | + | Rv1421 | 0.46 | -1.4 | |
| 1,596,710 | - | Rv1421 | 0.81 | -3.3 | |
| 1,596,753 | - | Rv1421 | 0.85 | -2.3 | |
| 1,596,783 | - | Rv1421 | 0.89 | -1.4 | |
| 1,596,960 | - | -0.5 | |||
| 1,597,485 | + | Rv1422 | 0.59 | -0.1 | |
| 1,597,486 | - | Rv1422 | 0.59 | -0.4 | |
| 1,597,770 | + | Rv1422 | 0.86 | -1.0 |
Or see this region's nucleotide sequence