Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1410c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,586,212	-				-0.5
1,586,300	+				-0.5
1,586,301	-				-1.3
1,586,343	-				-3.6
1,586,343	-				-1.6
1,586,352	+				-2.9
1,586,352	+				-1.7
1,586,352	+				-3.1
1,586,466	+		Rv1410c	0.16	-4.4
1,586,615	+		Rv1410c	0.26	-3.4
1,586,713	+		Rv1410c	0.32	-1.9
1,586,737	+		Rv1410c	0.34	-2.4
1,587,077	+		Rv1410c	0.56	-1.9
1,587,077	+		Rv1410c	0.56	-0.4
1,587,077	+		Rv1410c	0.56	-1.7
1,587,078	-		Rv1410c	0.56	-4.7
1,587,105	+		Rv1410c	0.57	-4.4
1,587,106	-		Rv1410c	0.58	-2.1
1,587,218	+		Rv1410c	0.65	+1.9
1,587,219	-		Rv1410c	0.65	-1.8
1,587,219	-		Rv1410c	0.65	-1.6
1,587,219	-		Rv1410c	0.65	-1.7
1,587,413	+		Rv1410c	0.77	-3.2
1,587,595	-		Rv1410c	0.89	-3.7
1,587,595	-		Rv1410c	0.89	-0.9
1,587,606	+		Rv1410c	0.90	-4.3
1,587,607	-		Rv1410c	0.90	+0.3
1,587,607	-		Rv1410c	0.90	-5.4
1,587,652	+				-2.7
1,587,653	-				+0.3
1,587,653	-				-3.7
1,587,653	-				-4.7
1,587,653	-				-2.3
1,587,696	+				-0.9
1,587,696	+				+1.9
1,587,696	+				-4.0
1,587,696	+				+1.9
1,587,697	-				-4.9
1,587,697	-				+1.9
1,587,697	-				-4.2
1,587,697	-				-4.4
1,587,697	-				-4.1
1,587,697	-				-3.3
1,587,720	-				-1.3
1,587,836	+				-2.0
1,587,943	+		Rv1411c	0.24	-5.1
1,588,009	-		Rv1411c	0.33	+0.9
1,588,095	-		Rv1411c	0.45	-3.0
1,588,095	-		Rv1411c	0.45	+1.9
1,588,148	+		Rv1411c	0.53	-1.9
1,588,149	-		Rv1411c	0.53	-1.1
1,588,185	+		Rv1411c	0.58	-2.9
1,588,482	+				-0.6