Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1331

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,499,684	+		Rv1330c	0.35	+0.0
1,499,808	+		Rv1330c	0.44	+1.9
1,499,808	+		Rv1330c	0.44	-0.9
1,499,809	-		Rv1330c	0.44	+0.3
1,499,812	+		Rv1330c	0.44	-0.0
1,499,813	-		Rv1330c	0.45	-0.3
1,499,813	-		Rv1330c	0.45	+0.0
1,499,813	-		Rv1330c	0.45	+0.2
1,500,003	+		Rv1330c	0.59	+0.9
1,500,003	+		Rv1330c	0.59	+0.3
1,500,481	-				-0.6
1,500,481	-				+2.9
1,500,481	-				+0.1
1,500,481	-				-0.2
1,500,694	-		Rv1331	0.11	-0.9
1,500,694	-		Rv1331	0.11	-1.3
1,500,784	+		Rv1331	0.40	-0.4
1,500,793	+		Rv1331	0.43	-0.4
1,500,794	-		Rv1331	0.43	-0.1
1,500,794	-		Rv1331	0.43	-1.4
1,501,347	+		Rv1332	0.64	+0.3
1,501,347	+		Rv1332	0.64	+0.0
1,501,523	+				-2.0
1,501,550	+				-1.3
1,501,551	-				+1.2
1,501,551	-				-0.2
1,501,836	+		Rv1333	0.23	+1.5
1,501,873	+		Rv1333	0.26	-0.8
1,501,874	-		Rv1333	0.27	+0.3