Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1281c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,432,566	+		Rv1280c	0.51	+1.9
1,432,567	-		Rv1280c	0.51	-0.7
1,432,567	-		Rv1280c	0.51	-0.8
1,432,703	-		Rv1280c	0.58	-1.2
1,432,974	+		Rv1280c	0.74	+0.6
1,432,975	-		Rv1280c	0.74	-1.2
1,432,975	-		Rv1280c	0.74	-0.1
1,432,975	-		Rv1280c	0.74	-0.6
1,433,023	-		Rv1280c	0.76	-0.7
1,433,321	+				-0.3
1,433,489	-				-1.3
1,433,786	-		Rv1281c	0.19	-0.5
1,434,488	-		Rv1281c	0.57	-1.2
1,434,524	-		Rv1281c	0.59	-2.1
1,434,587	-		Rv1281c	0.63	-1.1
1,434,955	+		Rv1281c	0.83	-0.2
1,435,133	+				-0.7
1,435,187	-				-0.5
1,435,366	+		Rv1282c	0.11	-1.1
1,435,367	-		Rv1282c	0.11	+1.9
1,435,594	+		Rv1282c	0.37	-0.2
1,435,595	-		Rv1282c	0.37	-1.5
1,435,770	-		Rv1282c	0.57	-0.4
1,436,007	+		Rv1282c	0.84	-0.9
1,436,037	+		Rv1282c	0.88	-1.1
1,436,097	-				-1.1
1,436,115	-				-0.7
1,436,175	-				+0.9
1,436,229	+				-0.9