Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1280c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,431,026	-		Rv1279	0.61	+0.1
1,431,029	+		Rv1279	0.61	-0.8
1,431,030	-		Rv1279	0.61	-0.8
1,431,030	-		Rv1279	0.61	-1.0
1,431,030	-		Rv1279	0.61	-0.4
1,431,277	+		Rv1279	0.77	-0.2
1,431,277	+		Rv1279	0.77	-0.8
1,431,299	+		Rv1279	0.78	+0.3
1,431,460	+		Rv1279	0.88	-0.7
1,431,591	+				+0.3
1,431,591	+				-0.2
1,431,592	-				-0.3
1,431,694	-				-1.3
1,431,694	-				+0.3
1,431,928	-		Rv1280c	0.15	-1.9
1,432,120	-		Rv1280c	0.26	-0.9
1,432,120	-		Rv1280c	0.26	-1.3
1,432,224	+		Rv1280c	0.31	-0.1
1,432,224	+		Rv1280c	0.31	-0.4
1,432,338	+		Rv1280c	0.38	-0.3
1,432,423	-		Rv1280c	0.43	-1.9
1,432,566	+		Rv1280c	0.51	+1.9
1,432,567	-		Rv1280c	0.51	-0.7
1,432,567	-		Rv1280c	0.51	-0.8
1,432,703	-		Rv1280c	0.58	-1.2
1,432,974	+		Rv1280c	0.74	+0.6
1,432,975	-		Rv1280c	0.74	-1.2
1,432,975	-		Rv1280c	0.74	-0.1
1,432,975	-		Rv1280c	0.74	-0.6
1,433,023	-		Rv1280c	0.76	-0.7
1,433,321	+				-0.3
1,433,489	-				-1.3
1,433,786	-		Rv1281c	0.19	-0.5