Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1276c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,425,336	+				+0.5
1,425,336	+				+0.8
1,425,344	+				-0.9
1,425,357	-				-0.4
1,425,404	+				-0.3
1,425,511	-		Rv1276c	0.15	-1.3
1,425,715	+		Rv1276c	0.58	-0.7
1,425,931	+				+0.2
1,425,957	-				-0.2
1,426,085	+				-0.6
1,426,085	+				-0.1
1,426,086	-				-0.9
1,426,089	+				+0.2
1,426,089	+				+0.3
1,426,090	-				+0.5
1,426,090	-				-1.0
1,426,090	-				-0.1
1,426,222	+				-0.4
1,426,223	-				-0.4
1,426,223	-				-0.0
1,426,223	-				-0.3
1,426,375	+		Rv1277	0.17	-1.0
1,426,414	+		Rv1277	0.20	-0.2
1,426,459	+		Rv1277	0.24	-0.5
1,426,506	+		Rv1277	0.27	-0.2
1,426,840	-		Rv1277	0.54	-1.5
1,426,868	+		Rv1277	0.56	+0.2