Experiment: 7H9 with Bedaquiline 0.15 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1272c and Rv1273c overlap by 4 nucleotides Rv1273c and Rv1274 are separated by 146 nucleotides Rv1274 and Rv1275 overlap by 4 nucleotides
Rv1272c: Rv1272c - Probable drugs-transport transmembrane ATP-binding protein ABC transporter, at 1,420,410 to 1,422,305
Rv1272c
Rv1273c: Rv1273c - Probable drugs-transport transmembrane ATP-binding protein ABC transporter, at 1,422,302 to 1,424,050
Rv1273c
Rv1274: Rv1274 - Possible lipoprotein LprB, at 1,424,197 to 1,424,754
Rv1274
Rv1275: Rv1275 - Possible lipoprotein LprC, at 1,424,751 to 1,425,293
Rv1275
Position (kb)
1422
1423
1424
1425 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 1421.320 kb on - strand, within Rv1272c at 1421.320 kb on - strand, within Rv1272c at 1421.509 kb on + strand, within Rv1272c at 1422.358 kb on - strand at 1422.567 kb on + strand, within Rv1273c at 1422.567 kb on + strand, within Rv1273c at 1422.568 kb on - strand, within Rv1273c at 1422.568 kb on - strand, within Rv1273c at 1422.793 kb on - strand, within Rv1273c at 1423.020 kb on + strand, within Rv1273c at 1423.213 kb on - strand, within Rv1273c at 1423.822 kb on - strand, within Rv1273c at 1423.822 kb on - strand, within Rv1273c at 1423.822 kb on - strand, within Rv1273c at 1423.886 kb on + strand at 1423.954 kb on - strand at 1424.055 kb on + strand at 1424.056 kb on - strand at 1424.192 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Bedaquiline 0.15 ug/mL remove 1,421,320 - Rv1272c 0.48 -1.6 1,421,320 - Rv1272c 0.48 -0.4 1,421,509 + Rv1272c 0.58 -1.4 1,422,358 - -2.3 1,422,567 + Rv1273c 0.15 -2.1 1,422,567 + Rv1273c 0.15 -1.2 1,422,568 - Rv1273c 0.15 -0.1 1,422,568 - Rv1273c 0.15 +1.9 1,422,793 - Rv1273c 0.28 -0.2 1,423,020 + Rv1273c 0.41 -1.6 1,423,213 - Rv1273c 0.52 -1.5 1,423,822 - Rv1273c 0.87 -0.8 1,423,822 - Rv1273c 0.87 -1.4 1,423,822 - Rv1273c 0.87 -2.1 1,423,886 + -2.0 1,423,954 - -0.8 1,424,055 + -2.7 1,424,056 - -0.4 1,424,192 + -0.2
Or see this region's nucleotide sequence