Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1270c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,418,073	+		Rv1268c	0.59	-0.1
1,418,074	-		Rv1268c	0.60	+0.0
1,418,244	+		Rv1268c	0.84	-0.2
1,418,244	+		Rv1268c	0.84	+0.8
1,418,244	+		Rv1268c	0.84	-0.7
1,418,245	-		Rv1268c	0.84	-0.4
1,418,245	-		Rv1268c	0.84	-0.1
1,418,245	-		Rv1268c	0.84	+0.2
1,418,245	-		Rv1268c	0.84	-0.7
1,418,380	+				+0.1
1,418,427	+				+0.4
1,418,433	+				-0.6
1,418,562	+				+0.3
1,418,580	+				-0.5
1,418,580	+				-0.3
1,418,580	+				-0.1
1,418,580	+				+0.2
1,418,581	-				+1.5
1,418,674	-		Rv1269c	0.25	+0.9
1,418,681	-		Rv1269c	0.27	+0.9
1,418,739	+		Rv1269c	0.43	-0.2
1,418,838	+		Rv1269c	0.69	-0.2
1,418,939	-				-0.4
1,419,003	+				+0.9
1,419,339	+		Rv1270c	0.44	+0.6
1,419,414	+		Rv1270c	0.54	+0.2
1,419,414	+		Rv1270c	0.54	-0.1
1,419,414	+		Rv1270c	0.54	+1.9
1,419,962	+				+0.2
1,419,992	+				+1.2
1,420,019	+		Rv1271c	0.17	-0.6
1,420,032	+		Rv1271c	0.21	-0.3
1,420,387	+				-0.9
1,420,429	+				-0.4
1,420,680	-		Rv1272c	0.14	-3.1