Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1184c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,323,743	-		Rv1183	0.74	+0.3
1,323,743	-		Rv1183	0.74	+1.3
1,323,752	+		Rv1183	0.74	+0.1
1,323,753	-		Rv1183	0.74	-0.5
1,323,844	+		Rv1183	0.77	-0.9
1,324,035	-		Rv1183	0.84	-0.1
1,324,035	-		Rv1183	0.84	+1.3
1,324,114	-		Rv1183	0.86	+0.3
1,324,347	+				+0.3
1,324,348	-				-0.1
1,324,666	-		Rv1184c	0.12	-1.7
1,324,779	+		Rv1184c	0.23	-2.1
1,324,780	-		Rv1184c	0.23	+1.9
1,324,780	-		Rv1184c	0.23	+0.9
1,324,951	-		Rv1184c	0.39	-2.6
1,325,005	+		Rv1184c	0.44	-2.8
1,325,005	+		Rv1184c	0.44	+0.9
1,325,005	+		Rv1184c	0.44	-3.2
1,325,006	-		Rv1184c	0.44	-2.6
1,325,006	-		Rv1184c	0.44	-2.8
1,325,006	-		Rv1184c	0.44	-2.7
1,325,006	-		Rv1184c	0.44	-2.2
1,325,007	+		Rv1184c	0.44	-2.3
1,325,008	-		Rv1184c	0.44	-1.8
1,325,236	+		Rv1184c	0.65	-2.1
1,325,349	+		Rv1184c	0.76	+0.9
1,325,695	-				-0.7
1,325,700	-				-1.0
1,325,724	+				-0.5
1,325,818	+				+0.1
1,326,011	-		Rv1185c	0.14	+3.9
1,326,113	+		Rv1185c	0.19	-0.7
1,326,115	+		Rv1185c	0.20	-0.1
1,326,116	-		Rv1185c	0.20	-0.6
1,326,275	+		Rv1185c	0.29	+0.3
1,326,389	+		Rv1185c	0.35	-0.2
1,326,389	+		Rv1185c	0.35	+1.2
1,326,465	-		Rv1185c	0.40	-0.9
1,326,542	-		Rv1185c	0.44	+0.3
1,326,564	-		Rv1185c	0.45	+1.2