Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1174c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,304,726	+		Rv1173	0.70	-0.4
1,304,727	-		Rv1173	0.70	+0.3
1,305,059	-		Rv1173	0.83	+0.5
1,305,100	-		Rv1173	0.84	+1.5
1,305,184	+		Rv1173	0.88	+0.3
1,305,236	+		Rv1173	0.90	+0.2
1,305,236	+		Rv1173	0.90	-0.4
1,305,481	+				+0.5
1,305,670	+				-0.1
1,305,670	+				+1.9
1,305,671	-				+0.1
1,305,673	+				-0.6
1,305,673	+				-1.2
1,305,673	+				-0.2
1,305,715	+		Rv1174c	0.14	-0.9
1,305,715	+		Rv1174c	0.14	-0.1
1,305,716	-		Rv1174c	0.14	-0.4
1,305,716	-		Rv1174c	0.14	-1.0
1,305,800	-		Rv1174c	0.39	-0.5
1,305,867	+		Rv1174c	0.59	+0.5
1,305,868	-		Rv1174c	0.60	-1.0
1,305,870	+		Rv1174c	0.60	+0.4
1,305,870	+		Rv1174c	0.60	-0.5
1,305,870	+		Rv1174c	0.60	-1.5
1,305,870	+		Rv1174c	0.60	-0.6
1,305,870	+		Rv1174c	0.60	-1.2
1,305,870	+		Rv1174c	0.60	-0.7
1,305,871	-		Rv1174c	0.61	-0.9
1,305,871	-		Rv1174c	0.61	-0.9
1,305,871	-		Rv1174c	0.61	-1.2
1,305,871	-		Rv1174c	0.61	-1.0
1,305,896	+		Rv1174c	0.68	-0.4
1,306,003	+				+0.2
1,306,004	-				-0.4
1,306,004	-				+1.2
1,306,004	-				+1.9
1,306,024	-				+0.3
1,306,024	-				-0.3
1,306,037	+				-1.3
1,306,037	+				-0.7
1,306,038	-				-0.0
1,306,144	+				+1.1
1,306,203	+				-0.3
1,306,205	+				+0.5
1,306,294	+				-1.2
1,306,295	-				-0.6
1,306,295	-				-0.1
1,306,359	-				-0.7
1,306,359	-				-0.4
1,306,359	-				-0.1
1,306,416	-		Rv1175c	0.11	-0.1
1,306,440	+		Rv1175c	0.12	+0.3
1,306,554	+		Rv1175c	0.17	+0.0
1,306,554	+		Rv1175c	0.17	-0.7
1,306,771	-		Rv1175c	0.28	-0.2
1,306,776	-		Rv1175c	0.28	-0.4
1,306,997	-		Rv1175c	0.39	-0.3