Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1055

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,176,483	+				-0.0
1,176,484	-				-0.2
1,176,484	-				-0.1
1,176,484	-				+2.0
1,176,484	-				-0.6
1,176,535	+				-0.2
1,176,553	+				+1.3
1,176,983	+		Rv1054	0.17	+2.4
1,176,984	-		Rv1054	0.18	-0.3
1,177,337	+		Rv1055	0.73	-0.8
1,177,549	+				+0.0
1,177,549	+				-0.5
1,177,605	-				+0.1
1,177,641	-				-0.2
1,177,671	+				-0.2
1,177,742	+		Rv1056	0.15	-0.7
1,177,760	+		Rv1056	0.17	+0.3
1,177,773	-		Rv1056	0.19	+1.0
1,177,775	+		Rv1056	0.19	-0.1
1,177,775	+		Rv1056	0.19	-0.5
1,177,776	-		Rv1056	0.19	-0.5
1,177,776	-		Rv1056	0.19	-0.4
1,177,776	-		Rv1056	0.19	-0.4
1,177,776	-		Rv1056	0.19	+0.5
1,177,776	-		Rv1056	0.19	+0.4
1,177,994	+		Rv1056	0.48	+1.4
1,177,995	-		Rv1056	0.48	-0.0
1,178,016	-		Rv1056	0.51	+0.1
1,178,136	-		Rv1056	0.66	-1.1
1,178,273	+		Rv1056	0.84	-0.5
1,178,273	+		Rv1056	0.84	-0.5
1,178,273	+		Rv1056	0.84	+1.4
1,178,274	-		Rv1056	0.84	-0.7
1,178,279	+		Rv1056	0.85	-0.0
1,178,280	-		Rv1056	0.85	-0.3
1,178,324	+				-0.3
1,178,325	-				-0.0