Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1053c

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,175,086	-				-1.4
1,175,112	+				-0.2
1,175,113	-				+0.0
1,175,113	-				-0.2
1,175,166	+				+2.0
1,175,167	-				-0.5
1,175,312	-				-0.2
1,175,379	+				-0.4
1,175,379	+				-0.1
1,175,379	+				-0.9
1,175,525	+				+0.2
1,175,525	+				-1.8
1,175,526	-				+0.1
1,175,531	+				-0.0
1,175,531	+				+1.0
1,175,531	+				-0.4
1,175,532	-				+2.0
1,175,538	-				-0.7
1,175,548	+				+0.4
1,175,706	-				+0.5
1,175,706	-				+0.4
1,175,832	-		Rv1052	0.28	+0.3
1,175,880	-		Rv1052	0.40	-0.1
1,175,972	+		Rv1052	0.64	+0.4
1,175,972	+		Rv1052	0.64	+0.5
1,175,972	+		Rv1052	0.64	+0.1
1,175,973	-		Rv1052	0.64	+2.0
1,176,012	+				+0.2
1,176,094	+				+1.5
1,176,094	+				+0.1
1,176,110	+				-0.2
1,176,210	-		Rv1053c	0.72	+0.5
1,176,483	+				-0.0
1,176,484	-				-0.2
1,176,484	-				-0.1
1,176,484	-				+2.0
1,176,484	-				-0.6
1,176,535	+				-0.2
1,176,553	+				+1.3
1,176,983	+		Rv1054	0.17	+2.4
1,176,984	-		Rv1054	0.18	-0.3