Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1049

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,171,471	+		Rv1048c	0.39	+0.4
1,171,611	+		Rv1048c	0.51	+0.2
1,171,612	-		Rv1048c	0.51	-0.0
1,171,663	-		Rv1048c	0.56	+1.3
1,171,689	+		Rv1048c	0.58	+0.5
1,171,689	+		Rv1048c	0.58	-0.1
1,171,689	+		Rv1048c	0.58	-0.5
1,171,896	+		Rv1048c	0.77	+0.3
1,171,983	+		Rv1048c	0.85	-0.3
1,172,384	+				-0.4
1,172,384	+				-0.3
1,172,422	+				-0.1
1,172,422	+				-0.2
1,172,422	+				+0.4
1,172,423	-				+2.0
1,172,423	-				+0.7
1,172,423	-				+0.1
1,172,462	-		Rv1049	0.17	-1.1
1,172,604	-		Rv1049	0.49	+0.4
1,172,849	-				+0.5
1,173,415	-		Rv1050	0.59	+2.5
1,173,710	+				-0.3
1,173,770	-				-0.5