Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1029

Experiment: 7H9 with Bedaquiline 0.15 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Bedaquiline 0.15 ug/mL
1,151,049	+		Rv1028c	0.75	+0.1
1,151,226	-		Rv1028c	0.82	-0.5
1,151,592	+				+1.0
1,151,731	-				+2.0
1,152,087	+				-1.0
1,152,163	-				+0.3
1,152,170	-				-0.5
1,152,210	+		Rv1029	0.12	-0.1
1,152,210	+		Rv1029	0.12	+0.5
1,152,211	-		Rv1029	0.12	-0.2
1,152,239	+		Rv1029	0.13	-0.4
1,152,239	+		Rv1029	0.13	+0.2
1,152,239	+		Rv1029	0.13	+0.7
1,152,239	+		Rv1029	0.13	-0.3
1,152,240	-		Rv1029	0.13	+2.5
1,152,258	+		Rv1029	0.14	+0.0
1,152,259	-		Rv1029	0.14	-1.4
1,152,379	-		Rv1029	0.21	-0.3
1,153,107	+		Rv1029	0.64	+0.0
1,153,107	+		Rv1029	0.64	+2.0
1,153,108	-		Rv1029	0.64	+0.6
1,153,196	-		Rv1029	0.69	-0.5
1,153,257	+		Rv1029	0.73	+1.5
1,153,305	+		Rv1029	0.75	-0.4
1,153,305	+		Rv1029	0.75	+1.0
1,153,305	+		Rv1029	0.75	-0.0
1,153,306	-		Rv1029	0.75	+0.4
1,153,419	+		Rv1029	0.82	+0.4
1,153,426	-		Rv1029	0.82	+0.4
1,153,488	+		Rv1029	0.86	+1.2
1,153,524	-		Rv1029	0.88	-0.0
1,153,651	+				+0.3
1,154,508	-		Rv1030	0.37	+0.1
1,154,508	-		Rv1030	0.37	+0.1